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Biomedical subjects

D L Vine

Publications and source records attributed to D L Vine.

At least 73 records · Page 4Linked to original sources

Subclavian artery stenosis treated by transluminal angioplasty: six cases.

Transluminal angioplasty (TLA) has been used in six patients with subclavian artery stenosis admitted to a large community hospital. Five patients had lesions proximal to the origin of the left vertebral artery, three of whom had angiographic evidence of subclavian steal syndrome. In all six, arteries were successfully dilated with only one complication of a hematoma at an arteriotomy site. In a 10 to 24-month follow-up, all six patients have remained totally asymptomatic without any further complications.

Adult↗

Echocardiographic mitral valve deformity in the mucopolysaccharidoses.

Previously reported echocardiographic abnormalities in patients with mucopolysaccaridosis and the Hunter-Hurler phenotype have stressed the similarity to calcific mitral stenosis despite the fact that mitral stenosis is a relatively uncommon manifestation of this disease. The purpose of this report is to describe the echocardiographic abnormalities in five patients with the Hunter-Hurler phenotype who had no clinical evidence of mitral stenosis. All had abnormal thickening of the mitral valve leaflets and one had echoes suggestive of calcification of the mitral annulus. All patients had normal electrocardiograms and roentgenographic cardiothoracic ratios, and two patients had no cardiac murmur. The high frequency of valvular deformity in this disease and the sensitivity of echocardiography in detecting these deformities suggest that echocardiography should be performed in the evaluation of patients with mucopolysaccharidosis. When echocardiographic evidence of valvular deformity is obtained, consideration should be given to bacterial endocarditis prophylaxis.

Adolescent↗

Repair of mycotic aneurysms of the aorta involving the aortic valve.

This report summarizes our successful management of 6 patients who underwent repair of mycotic aneurysms of the ascending aorta within a four-year period. Repairs have been successful despite involvement of as much as two-thirds of the circumference of the aortic valve annulus, involvement of the origin of the right coronary artery, and development of heart block. Three patients required surgical intervention because of hemodynamic decompensation before they had completed antibiotic therapy for endocarditis. In 3 patients, the aneurysm was buttressed with the valve skirt so that aneurysm repair and valve replacement were accomplished in continuity. In 2 patients, the aneurysm was repaired separately and the valve seated on the repair. In 1 patient, a large defect between the left and right coronary arteries was repaired with a woven Dacron patch secured to the valve skirt. The valve was seated to the left ventricle and the graft to the aorta. There were no operative or postoperative deaths. Our data suggest that mycotic aneurysms of the aortic annulus can be successfully repaired despite extensive damage.

Adolescent↗

Effect of respiration on the echocardiogram in children with cystic fibrosis.

Respiration-related cyclic variation was noted in echocardiographic measurements of right and left ventricular end-diastolic dimension. D-E amplitude of the anterior mitral leaflet, and mitral valve E-F slope in 26 children with cystic fibrosis. The observed echographic changes seem to be an exaggeration of the normal physiologic variation seen with respiration. In children with advanced respiratory disease, airway obstruction, rather than cor pulmonale, may be responsible for this exaggeration.

Adolescent↗

The effect of supine rotation on left ventricular dimensions in man: a study using radio-opaque epicardial markers.

It has been reported that patient rotation into the left lateral decubitus position (30 degrees rao) produces significant changes in the regression equations used for left ventricular volume determination and that normal values for echocardiographic left ventricular dimensions obtained from supine patients differ from those obtained after rotation. The purpose of this study was to establish whether patient rotation is associated with changes in left ventricular size and systolic function. The distances between left ventricular epicardial markers attached at the time of cardiac surgery were measured using biplane cineradiography in 14 patients in order to determine left ventricular dimensions before and after rotation. Supine epicardial left ventricular dimensions were not significantly different from those obtained with the patient rotated 30 degrees rao. These results suggest that reported changes in invasive and noninvasive measurements of left ventricular function associated with patient rotation are not primarily due to changes in left ventricular size.

Adult↗

Late isolated left ventricular tamponade. Clinical, hemodynamic, and echocardiographic manifestations of a previously unreported postoperative complication.

A unique case of late postoperative left ventricular tamponade, hemodynamically indistinguishable from severe left ventricular failure, is reported in a patient 1 month after an apparently uncomplicated aortic valve replacement. An echo-free space behind the left ventricle led to surgical exploration and successful resolution of the disease process. To our knowledge, this is the first documented case of isolated left ventricular tamponade in the literature. The findings highlight the importance of postoperative echocardiography in the evaluation of the patient having cardiac surgery.

Aneurysm, Infected↗

Immediate effect of contrast medium injection on left ventricular volumes and ejection fraction. A study using metallic epicardial markers.

The immediate effect of contrast medium injection on left ventricular (LV) volume, stroke volume (SV) and ejection fraction (EF) was evaluated from postoperative LV biplane cineangiograms of 10 patients with 4-6 epicardial markers placed at the time of coronary artery surgery. After calibrating marker distances with respect to volume (r = 0.97-0.99) over one cardiac cycle for each patient, regression equations were used to compute LV volume from marker measurements for beats prior to, during and following injection. End-diastolic volumes (EDV) prior to injection ranged from 93-263 ml and did not change significantly with injection. End-systolic volumes (ESV) showed a mean decrease of 7.3 ml by beat 7 following injection; this was of borderline significance. Similarly, there was no significant change of SV or EF until beat 7 when there were small but significant increases of 6.4 ml and 0.04, respectively. The injection of moderate amounts of contrast in man does not cause significant changes in LV volume or EF through the sixth post-injection beat.

Cardiac Output↗

Quantitative measurement of left ventricular volumes in man from radiopaque epicardial markers.

The distances between three or four radiopaque markers located on the left ventricular epicardial surface at the apex and in the region of the minor axes in 22 subjects showed close correlations with left ventricular chamber radii, length, volume and wall thickness determined from biplane angiograms over the range of stroke volume. The markers were previously placed during heart surgery. Regression equations relating the distances between epicardial markers and chamber volumes were used to predict volumes for other beats. There was close agreement of end-diastolic, end-systolic, and stroke volumes as determined by the angiographic and epicardial marker methods for premature atrial contraction beats and post premature contraction beats, and in studies performed during rest and exercise. Time-volume curves determined by the epicardial marker and angiographic methods were similar. It is concluded that epicardial marker measurements can be used to quantitate beat-to-beat left ventricular chamber volume and dimension changes.

Angiocardiography↗