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Biomedical subjects

D L Herbert

Publications and source records attributed to D L Herbert.

25 records · Page 2Linked to original sources

Correlation of radiographic and histologic findings in arterial calcification.

Intimal calcific atherosclerosis may lead to diminished organ perfusion, whereas medial calcification (Mönckeberg type) is of no physiologic significance. Thirty-nine excised arteries were studied by correlating specimen radiographs with transverse histologic sections to determine whether intimal and medial calcification could be reliably distinguished by radiographic criteria. The calcification was correctly localized in 92% of the arteries studied. Intimal calcification was usually irregular and patchy, whereas medial calcification was regular and diffuse. In one case, extensive medial calcification obscured intimal disease. Plain radiographs may be a useful way to follow progression, regression and the effects of therapy on vaso-occlusive disease in certain high-risk patients.

Aorta↗

Blood flow mapping in the human liver by the xenon/CT method.

In the noninvasive, nonradioactive xenon/CT method of blood flow measurement, xenon gas is inhaled, and the temporal changes in radiographic enhancement produced by the inhalation are measured by sequential CT; time-dependent xenon concentration within various tissue segments is then used to derive local blood flow maps. The usefulness of the method in the assessment of local cerebral blood flow has been documented. In this paper we explore its application to blood flow measurement in the human liver. In our preliminary clinical studies, hepatic blood flow ranged from 50 to 120 ml/100 cc/min in normal and adequately supplied tissue, and lower flow values were observed in tissue with abnormal function. The advantages and limitations of the method in such applications are discussed.

Adult↗

Stereotactic brain surgery: a method for rapid and precise positioning of a target in the Todd-Wells stereotactic instrument.

We describe an improved method for positioning the head for stereotactic brain surgery of aneurysms. The method uses a mathematical calculation and requires some physical modifications in the Todd-Wells stereotactic apparatus. This procedure achieves (1) a reduction in the number of angiograms needed and (2) an increase in the speed and accuracy of positioning. The technique has been applied to operations on live dogs.

Humans↗

Legal issues in the delivery of worksite health promotion.

Employee health promotion programs typically involve one or more of the following: (1) education programs, (2) cholesterol, blood pressure, diabetes, or other similar screening programs, (3) smoking cessation programs, (4) drug/alcohol testing and counseling programs, (5) exercise facility or activity programs, and (6) recreational activity programs. The authors examine potential legal implications of these activities. This chapter is intended for those attempting to define and establish these programs or to focus and operate them without undue conflict or legal system involvement.

Health Education↗