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Biomedical subjects

D Korn

Publications and source records attributed to D Korn.

At least 91 records · Page 5Linked to original sources
PubMed1971

Control of plasmid replication in Escherichia coli: correlation of the membrane site of DNA replication with the bacterial segregation unit.

The fate of parental lambda genomes after superinfection of homoimmune lysogenic cells was studied. The data confirm a previous observation that in the presence of the lambda repressor, superinfecting lambda DNA does not become associated with replication sites on the bacterial cell membrane. Under these conditions, the nonreplicating, superinfecting phage genomes do not become associated with the bacterial segregation unit. These results support the concept that the attachment of DNA to the bacterial membrane at specific sites is involved in the control of both chromosome replication and segregation, as predicted by the replicon hypothesis.

Autoradiography↗
PubMed1966

Impairment of Temperate Bacteriophage Adsorption by Brief Treatment of Escherichia coli with Dilute Solutions of Ethylenediaminetetraacetate.

Protass, Jay J. (National Institute of Arthritis and Metabolic Diseases, Bethesda, Md.), and David Korn. Impairment of temperate bacteriophage adsorption by brief treatment of Escherichia coli with dilute solutions of ethylenediaminetetraacetate. J. Bacteriol. 91:143-147. 1966.-Cells of Escherichia coli K-12 treated for 2 min with 2 x 10(-4)m ethylenediaminetetraacetate (EDTA) are unable to adsorb the temperate bacteriophages lambdavir and 434 but show no impairment of their ability to adsorb T-even phages or T5. This finding is consistent with the hypothesis that there are basic structural differences between the cell-wall receptors involved in the adsorption of the temperate and T classes of coliphages.

Journal Article↗