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Biomedical subjects

D K Montague

Publications and source records attributed to D K Montague.

13 recordsLinked to original sources
PubMed1992

Early experience with the controlled girth and length expanding cylinder of the American Medical Systems Ultrex penile prosthesis.

A prospective study was done to evaluate length expansion characteristics of the AMS Ultrex penile prosthesis cylinder intraoperatively and in the early postoperative period. A total of 50 patients 30 to 74 years old (mean age 55.2 years) underwent implantation of this device. Intraoperative changes in the pubis to mid glans distance between deflation and inflation ranged from 1 to 4 cm. (mean 1.9). Postoperative followup measurements were obtained in 46 patients at 1 to 15 months (mean 4). There was a 1 cm. decrease in the amount of postoperative length expansion for 6 patients, while length expansion increased by 1 cm. for 12 and for 28 the postoperative length expansion was the same as the intraoperative length expansion.

Adult↗
PubMed1979

Psychogenic urinary retention.

Six cases (5 females and 1 male) of unexplained urinary retention are reported. The diagnosis of psychogenic urinary retention was considered after negative medical, urologic, urodynamic, and neurologic evaluations. This diagnosis was then confirmed by psychiatric consultation. Urinary retention was managed by combining biofeedback-monitored relaxation and specific imagery techniques with intermittent self-catheterization on a fixed schedule. Psychotherapy, pharmacotherapy, and behavior therapy were also utilized with good to excellent short-term results.

Adolescent↗
PubMed1979

Urethral pressure profiles before and after Ornade administration in patients with stress urinary incontinence.

Urethral pressure profilometry was done on 12 women with stress urinary incontinence and in 6 women with no history of incontinence, before and 1 to 2 hours after the administration of Ornade. Eleven of the 12 women with stress urinary incontinence had increases in the maximal urethral pressure of 20 per cent or more over the control value. Only 1 of the 6 control women exhibited an increase in the maximal urethral pressure of greater than 20 per cent after the administration of Ornade. It is believed that the phenylpropanolamine component of Ornade stimulates alpha-adrenergic receptors at the vesical neck and in the proximal urethra to achieve the therapeutic effect of reducing or eliminating stress urinary incontinence. This drug is preferred over ephedrine primarily because of its sustained release, allowing dosage twice a day, and because of its relative freedom from side effects.

Chlorpheniramine↗
PubMed1979

Half and total body radiation for carcinoma of the prostate.

Despite recent advances in the treatment of stage D carcinoma of the prostate many patients become refractory to all therapeutic modalities. Progressive and incapacitating pain is one of the most difficult symptoms to manage. Ten patients with severely symptomatic metastatic adenocarcinoma of the prostate have been treated with either single or sequential doses of half body radiation using 800 rad delivered by a Linac 10 mV linear accelerator. There were 15 courses of half body radiation delivered and a good to excellent response was noted in 11 instances. Results often were immediate and the duration of the response was variable. Treatment was well tolerated with no fatal complications. Half and total body radiation appears to offer significant palliation and its use with other forms of therapy warrants further investigation.

Humans↗
PubMed1979

Diagnostic evaluation, classification, and treatment of men with sexual dysfunction.

During a two-year period, 165 men were evaluated for sexual dysfunction. Most evaluations were conducted on an outpatient basis and required two separate visits. Fifty-one per cent, 47 per cent, and 2 per cent of the patients were found to have functional disorders, organic disorders, and incomplete evaluations, respectively. Treatment recommendations were tailored to each patient using information gathered during the diagnostic evaluation.

Adolescent↗
PubMed1977

The role of adjunctive nephrectomy in patients with metastatic renal cell carcinoma.

The results of therapy for 78 patients with disseminated renal cell carcinoma are evaluated. Symptoms related to the primary tumor were noted in only 28 per cent of the patients and were not difficult to manage in those patients not undergoing nephrectomy. Adjuctive nephrectomy, therefore, is a more appropriate term than palliative nephrectomy when referring to removal of the primary tumor as part of an aggresive combined therapeutic approach. Of patients receiving an adjunctive nephrectomy those with osseous metastases only had a better 1-year survival rate (36 per cent) than those with metastases to other sites (18 per cent). Complete regression of metastases was noted in 12 per cent of patients treated with medroxyprogesterone acetate and adjunctive nephrectomy. The role of adjunctive nephrectomy combined with embolic infarction, hormonal therapy, chemotherapy and/or immunotherapy is discussed.

Adenocarcinoma↗
PubMed1977

Experience with a urinary sphincter prosthesis.

From February 1974 through April 1975, ten patients have had a Scott urinary sphincter prosthesis implanted for the relief of urinary incontinence. In nine of the patients, incontinence was due to trauma of the sphincter, and in one patient, incontinence was due to a neurogenic bladder. Four patients have been totally continent following operation and, thus far, have not required additional operative procedures. Two additional patients were continent after the initial implant, but incontinence recurred because of mechanical failure of the device. Both patients are again continent following replacement of the defective portion of the prosthesis. Four patients have been classified as failures. Infection was the cause of failure in three of these patients, and in the fourth patient with a neurogenic bladder, failure was due to uncontrollable detrusor hyperreflexia.

Adult↗
PubMed1976

Primary neoplasms in vesical diverticula: report of 10 cases.

Of 10 patients with primary neoplasms in vesical diverticula 2 died within 2 years of diagnosis and 8 survived more than 2 years (6 free of disease). These results are contrasted to the relatively poor survival of patients reported in other series. Early diagnosis and adequate treatment are stressed.

Aged↗
PubMed1976

Stress incontinence: conservative therapy with sympathomimetic drugs.

There were 77 women with mild to moderate stress urinary incontinence treated with the sympathomimetic agent, phenylpropanolamine hydrochloride, combined with chlorpheniramine maleate and isopropamide iodide in a sustained release capsule (Ornade). The majority of these patients achieved significant improvement 3 months to 3 years after beginning therapy. A trial of conservative therapy is advisable for stress incontinence, especially when symptoms are mild or when the patients are in a poor risk category. Similar management of post-prostatectomy stress incontinence in men was disappointing. However, the occasional excellent results in patients with mild symptoms appear to justify a trial of conservative therapy before considering operative intervention in this group of patients.

Administration, Oral↗
PubMed1975

Retroperitoneal germ cell tumors with no apparent testicular involvement.

Five men with retroperitoneal germ cell tumors and no apparent testicular involvement are described. Each case has a different feature lending support to one of the various theories concerning the origin of these tumors. Patients with such a tumor are best managed without removal or biopsy of either testis. Careful, periodic re-examination of both testes is suggested. Only if a testis subsequently becomes abnormal is its removal indicated.

Adult↗