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Biomedical subjects

D K Ford

Publications and source records attributed to D K Ford.

74 records · Page 5Linked to original sources

Synovial mononuclear cell responses to rubella antigen in rheumatoid arthritis and unexplained persistent knee arthritis.

3H-thymidine uptake responses by synovial mononuclear cells to rubella antigen were studied in 10 patients with rheumatoid arthritis and in 8 patients with unexplained arthritis confined to knee joints. The synovial cells of only 1 rheumatoid subject responded to rubella. In only 1 of the patients with knee joint arthritis was the response to rubella greater than to other tested antigens. Peripheral blood leukocytes did not respond to rubella in either patient. Rubella virus was isolated from the knee joints of both patients.

Adolescent↗

Cell-mediated immune responses in patients with recurrent arthritis following rubella immunization.

Six young adult women with recurrent rubella arthritis after HPV-77 DE/5 rubella immunization were studied. Lymphocyte responses to rubella and mumps antigens, and phytohemogglutinin and pokeweed mitogens, were measured in these patients and in 20 immunized hospital employees who did not develop arthritis. All 6 arthritic subjects had pre-immunization hemagglutination inhibition titers of less than 1:8 and their lymphocyte responses to rubella antigen were significantly elevated when compared with those members of the control group with a similar pre-immunization titer of less than 1:8. No significant differences between the 2 groups were found in the other lymphocyte responses.

Adult↗