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Biomedical subjects

D Jaspersen

Publications and source records attributed to D Jaspersen.

At least 19 recordsLinked to original sources
PubMed1992

[Endoscopic Doppler ultrasound in gastroduodenal ulcer hemorrhage].

AIMS: Investigation of the information value of endoscopic Doppler ultrasonography of the base of the ulcer in comparison with visual endoscopic assessment of bleeding gastroduodenal ulcers using the Forrest classification. STUDY DESIGN: Open prospective comparative study involving 30 patients with acutely bleeding gastroduodenal ulcers. Where Doppler ultrasonography revealed an artery in the base of the ulcer, injection with epinephrine and polidocanol was administered. Follow-up examinations were performed on day 2 and after 4 weeks. RESULTS: Endoscopic Doppler ultrasonography reliably identifies the vessels responsible for bleeding from gastroduodenal ulcers, in particular in lesions with stigmata of recent bleeding (Forrest II), but also in ulcers with no such stigmata but a history of bleeding (Forrest III). In addition, Doppler ultrasonography also allows the results of injection therapy to be determined. CONCLUSION: Endoscopic Doppler ultrasonography makes possible the rapid and efficient identification of invisible vessels in the ulcer floor responsible for bleeding.

Adult↗
PubMed1992

[Endoscopic Doppler ultrasonography in lower intestinal bleeding:vascular diagnosis and monitoring of therapy].

Endoscopic Doppler sonography is a relatively new method for evaluating the sources of intestinal bleeding. For the most part our experiences derived from cases of gastroduodenal ulcer bleedings, in which Doppler sonography permits the identification of arterial vessels relevant for recurrent ulcer bleedings as well as follow-up of therapy after sclerosing. In the lower intestinal tract endoscopic Doppler has, however, only rarely been used, e.g. for diagnosing vascular malformations. This method is of theoretical interest for evaluating colorectal sources of bleeding but is nonetheless of some practical importance, as our investigations of angiodysplasias, ulcers of the rectum and polyps demonstrate.

Adult↗
PubMed1992

[Gastrointestinal manifestations of systemic lupus erythematosus: symptoms, diagnosis and differential diagnosis].

Systemic lupus erythematosus (SLE) is a chronic rheumatic systemic disease of unknown etiology, with multiple organ involvement. About one-half of the patients have gastrointestinal manifestations, the symptomatology, diagnostic evaluation and differential diagnosis of which are discussed in this review. Inflammatory ulcerous changes in the gastrointestinal tract are here of primary clinical importance, not least on account of the frequent use of NSAID and corticosteroid medication. Although liver-specific laboratory parameters are often elevated they usually have no clinical significance.

Autoimmune Diseases↗
PubMed1992

[Stent implantation in post-stenotic retention pneumonia caused by inoperable bronchial carcinoma].

The 65 year old patient referred to in this report has been suffering from an inoperable squamous cell carcinoma of the right superior lobe of the lung for the last two years. After therapeutic irradiation the disease subsided temporarily. Subsequently the patient became severely ill and was referred to hospital with high fever and refractory pneumonia. X-ray film revealed atelectasis of the right superior and central lobes and a pneumonic infiltration of the right inferior lobe. Bronchoscopy showed complete tumour stenoses of the superior and central lobes. The lower lobe of the lung was visualised as subtotally stenosed and obstructed by pus. Despite pathogen-directed antibiosis the poststenotic retention pneumonia did not heal. After laser recanalisation of the right inferior lobe we implanted an endobronchial stent. Subsequently, the pneumonia receded and the patient survived for five months relatively free from complaints.

Airway Obstruction↗
PubMed1992

[Proctoscopic Doppler ultrasound in diagnosis and therapy of symptomatic first degree hemorrhoids ].

Within the framework of a prospective study two comparable collectives with each 62 patients and symptomatic first grade hemorrhoidal disease were examined. Guiding symptom was painless hematochezia. The hemorrhoids of collective A were evaluated with the aid of transproctoscopic Doppler ultrasound. The depth of the vessels was determined and a Doppler located injection therapy was performed. The patients of collective B were only investigated by means of proctoscopy and sclerosed without Doppler. Sclerosing injection was carried out in all cases with 6 ml Phenylamygdalic oil by 3, 7 and 11 o'clock lithotomy position. Success of therapy was controlled in all patients 2 weeks later Doppler sonographically. In 87% of the Doppler controlled treated patients the hemorrhoids were completely eliminated and no more arterial blood flow could be scanned. On the contrary only 37% of the initially not Doppler scanned patients were cured. Endoscopic Doppler ultrasound is and effective method in evaluation and treatment of symptomatic first grade hemorrhoids.

Blood Flow Velocity↗