Succinic acid production by rumen bacteria. II. Radioisotope studies on succinate production by Ruminococcus flavefaciens.
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Biomedical subjects
Publications and source records attributed to D J Walker.
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Lower extremity wounds related to venous insufficiency are increasing. As the number of adults over the age of 65 increases, so do wounds related to changes in the vascular system. Venous stasis wounds can present as a real challenge to experienced practitioners. This article describes the many factors associated with venous wounds as well as the need for a comprehensive treatment plan.
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We have studied patients with acute hot joints presenting to general practice, casualty and inpatient rheumatology services. Their investigation, management and outcome were measured against guidelines. Different spectra of disease were seen in the different health care settings. The guidelines were not adhered to for crystal arthritis, particularly when it affected the first metatarso-phalangeal joints. The guidelines were broadly adhered to and useful for other joints, especially where septic arthritis was considered to be the likely diagnosis. We found no benefit on outcome from adhering to the guidelines. There was a tendency for the outcome to be worse where the guidelines were followed in full, suggesting that more investigations are performed in the more difficult cases. We conclude that drawing up guidelines for patient management is difficult even in an area where there is broad medical agreement.