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Biomedical subjects

D J Salberg

Publications and source records attributed to D J Salberg.

At least 19 recordsLinked to original sources
PubMed1986

Taking the byte: more thoughts about microcomputers.

Appropriate use of computerized data bases can be useful to the P & T Committee. Although the use of computerized literature searches has been recognized, the microcomputer can be used for other important and time-saving applications. One software system in use at a VA Medical Center is presented here, and its function are described. Potential uses and future applications are discussed.

Computers↗
PubMed1984

P & T Committee roundtable discussion: Great Lakes region. Part II.

A series of regional roundtable discussions regarding the successful operation of Pharmacy and Therapeutic (P & T) Committees has been conducted by Hospital Formulary. Representation from private hospitals, university and teaching hospitals, as well as Veterans Administration Medical Centers has been achieved to ensure that different aspects of P & T Committee performance are demonstrated. Issues such as committee profile, constituency, function, and mechanics are discussed, as are criteria for establishing a successful formulary within an institution. The sessions were taped and the edited transcription is provided in the following article.

Great Lakes Region↗
PubMed1984

Cost of wastage in a hospital intravenous admixture program.

The wastage in a hospital centralized pharmacy intravenous admixture program was assessed. The loss rate was similar during two separate 36-day study intervals, averaging 6.2% of intravenous admixture preparations, accounting for an estimated loss of $26,077 for the year. Discontinuation of intravenous therapy accounted for half of the returned intravenous admixtures. Patient unavailability, drug changes, and malfunction of intravenous equipment were also causes for returns. Improved communication between hospital ward units and pharmacy personnel as well as increased flexibility in admixture preparation scheduling may reduce wastage. Ultimately, pharmacists assigned to individual ward units as part of the unit-dose pharmacy dispensing system may resolve the problem.

Analysis of Variance↗
PubMed1983

Comparison of cultures of human lymphocytes obtained following NH4Cl induced red blood cell lysis and Ficoll-Hypaque density gradient centrifugation.

Lymphocyte thymidine uptake in leucocytes prepared by NH4Cl induced RBC lysis was compared with that of lymphocytes obtained following Ficoll-Hypaque centrifugation using polynomial regression dose response curves which adjusted for inherent subject variability. Eleven male subjects were studied. Heparinized blood was either layered in Ficoll-Hypaque or treated with 0.87% NH4Cl to induce RBC lysis. Phytohemagglutinin-P (PHA) dose response curves were determined for each subject using triplicate 5 day cultures. For each subject, at each Pha concentration ranging from 12.5 to 167micrograms/ml, triplicate mean cpm of Ficoll-Hypaque treated lymphocytes and NH4Cl treated lymphocytes were compared by the 2 tailed Student's T test. Responses of cultures of NH4Cl treated lymphocytes were significantly different (less than 0.05) from the responses of cultures of Ficoll-Hypaque treated lymphocytes for at least 2 PHA doses in 8 of the 11 subjects. The quadratic dose response curves were also significantly different (p less than 0.05) for 9 of the 11 subjects. A repeated measures quadratic regression was used to determine the best fit dose response curves for each of the experimental conditions. For Ficoll-Hypaque treated lymphocytes, mean cmp=44,977+1400.4 (PHA concentration)-5.90 (PHA concentration)2+ subject effect; s.e.=22,256; for NH4Cl treated lymphocytes, mean cpm=58,039+1022.8(Pha concentration)-5.32 (PHA concentration)2+ subject effect; s.e.=37,966. The p values from the F tests for significance of these quadratic regressions are different, F=1.91, d.f.=30,30; p less than 0.001. The lack of significance of the NH4Cl treated lymphocytes' does response quadratic regression and its larger s.e. indicates that the NH4Cl treated lymphocyte culture dose response curve is less predictable than that of Ficoll-Hypaque treated lymphocytes.

Ammonium Chloride↗