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Biomedical subjects

D J Sahn

Publications and source records attributed to D J Sahn.

At least 271 records · Page 15Linked to original sources
PubMed1978

Real-time cross-sectional echocardiographic imaging and measurement of the patent ductus arteriosus in infants and children.

While echocardiography has been used to noninvasively document indirect effects on the heart of left-to-right shunting through a patent ductus arteriosus, no noninvasive technique has been developed to image the duct itself. In this study, 35 sequential studies were performed on 28 patients with a mechanical sector scanner to image the distal pulmonary artery and its bifurcation by scanning along the axis of the right ventricular outflow tract. Cross-sectional imaging, just superior to the take-off of the right pulmonary artery, provided visualization of the patent ductus as a distal continuation of the pulmonary artery connecting to the descending aorta. Ductal visualization by cross-sectional echo was validated by saline echo contrast observations of right-to-left and left-to-right shunting through the duct in 14 patients, by surgical observations in 11, angiographic observations in 13 and autopsy observations in three. Angiographic size of the ductus arteriosus, whether constricted or widely patent, tortuous or straight, was predicted correctly and echo/angiographic correlations for smallest inner ductal dimension were excellent (r = 0.97). This study provides a method for and validates the direct imaging of the ductus arteriosus and suggests that cross-sectional echocardiography can accurately predict ductal contour and quantitative ductal cross-sectional size noninvasively.

Adolescent↗
PubMed1978

Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements.

Four hundred M-mode echocardiographic surveys were distributed to determine interobserver variability in M-mode echocardiographic measurements. This was done with a view toward examining the need and determining the criteria for standardization of measurement. Each survey consisted of five M-mode echocardiograms with a calibration marker, measured by the survey participants anonymously. The echoes were judged of adequate quality for measurement of structures. Seventy-six of the 400 (19%) were returned, allowing comparison of interobserver variability as well as examination of the measurement criteria which were used. Mean measurements and percent uncertainty were derived for each structure for each criterion of measurement. For example, for the aorta, 33% of examiners measured the aorta as an outer/inner or leading edge dimension, and 20% measured it as an outer/outer dimension. The percent uncertainty for the measurement (1.97 SD divided by the mean) showed a mean of 13.8% for the 25 packets of five echoes measured using the former criteria and 24.2% using the latter criteria. For ventricular chamber and cavity measurements, almost one-half of the examiners used the peak of the QRS and one-half of the examiners used the onset of the QRS for determining end-diastole. Estimates of the percent of measurement uncertainty for the septum, posterior wall and left ventricular cavity dimension in this study were 10--25%. They were much higher (40--70%) for the right ventricular cavity and right ventricular anterior wall. The survey shows significant interobserver and interlaboratory variation in measurement when examining the same echoes and indicates a need for ongoing education, quality control and standardization of measurement criteria. Recommendations for new criteria for measurement of M-mode echocardiograms are offered.

Aorta↗
PubMed1978

Echocardiographic diagnosis of atrial septal aneurysm in an infant with hypoplastic right heart syndrome.

Echocardiographic findings are described in a patient with hypoplastic right heart syndrome (pulmonary atresia type with intact ventricular septum and small right ventricular cavity) who had an associated atrial septal aneurysm. An unusual appearance of echoes behind the aorta bulging into the left atrium in diastole on both the M-mode and cross-sectional echo suggested this diagnosis prior to cardiac catheterization. The angiographic findings confirmed the diagnosis of right ventricular hypoplasia, pulmonary atresia and the large atrial septal aneurysm. The infant died after surgery and the atrial septal aneurysm was observed at autopsy. The importance of the diagnosis of the atrial septal aneurysm and its association with restriction of right-to-left atrial shunting prompts this report.

Cardiac Catheterization↗
PubMed1978

Clinical applications of real-time two-dimensional scanning in congenital heart disease.

Real-time two-dimensional visualization of cardiac anatomy has been a major advance in the noninvasive evaluation of congenital heart disease. Performed from precordial or suprasternal notch sites, the techniques allow noninvasive evaluation of the cardiac chambers, atrioventricular valves, and great arteries for the diagnosis of common and complex forms of congenital heart disease. Two-dimensional real-time echocardiography, therefore, can be expected to become an integral part of the noninvasive diagnosis and serial followup of children and infants with congenital heart disease.

Aortic Valve Stenosis↗
PubMed1978

Successful palliation using partial cardiopulmonary bypass in a two-day-old infant with type B interruption of the aortic arch.

Partial cardiopulmonary bypass from the pulmonary artery to the descending aorta was used successfully for resuscitation and aortic arch reconstruction in a 2-day-old infant with type B interrupted aortic arch. Partial cardiopulmonary bypass interrupted the fatal progression to acidosis and death caused by hypoperfusion of structures distal to the ductus arteriosus in this "ductus dependent" infant, and this approach provided time for an accurate dissection and anastomosis. The natural history, pathophysiology, and currently available surgical alternatives are considered in suggesting a possible role for partial bypass in the treatment interrupted aortic arch.

Acidosis↗
PubMed1977

Echocardiographic detection and management of patent ductus arteriosus in neonates with respiratory distress syndrome: a two-and one-half year prospective study.

A prospective 2 1/2 year study of 50 infants with combined respiratory distress syndrome (RDS) and patent ductus arteriosus (PDA) was undertaken to determine whether echocardiographic measurements combined with clinical assessment could be used to select those infants who needed cardiac treatment. From a pilot study, criteria were adopted to use digoxin in the treatment of infants with evidence of congestive cardiac failure and/or a left atrial dimension 1.5 times normal size, and to ligate the PDA in those with unremitting congestive cardiac failure and a left atrial dimension persistently twice normal. Left atrial, left ventricular, and aortic dimensions, left atrial to aortic ratio, and mean Vcf were echocardiographically determined. Forty-six per cent of the 50 infants with PDA required digoxin administration, and 18 per cent of the total group was operated. The long-term mortality for the total group was 12 per cent (6 of 50) and mortality was 33 per cent (3 of 9) for the operated group. Results showed that absolute left atrial dimension, particularly if recorded in two dimensions, most accurately predicted those infants who would develop congestive cardiac failure or failure that would become medically unmanageable.

Aorta↗
PubMed1977

Cross-sectional echocardiographic features of Ebstein's anomaly of the tricuspid valve.

Multicrystal real time-motion echocardiographic studies of 10 patients with Ebstein's anomaly of the tricuspid valve are reported. Eight patients also underwent hemodynamic and angiographic study. All but one of the patients had inferior and leftward displacement of the tricuspid valve. In seven patients multiple echoes were obtained from the tricuspid valve, all seven manifested elongated tricuspid valve leaflets, and in six the leaflets were thickened. Excessive excursion of the tricuspid valve was noted in five patients and a "whipping" motion seen in three. Nonspecific findings in nine patients included an increased right ventricular dimension and systolic anterior septal motion. Thus, cross-sectional echocardiography provides distinctive diagnostic findings that are specific for Ebstein's anomaly.

Adolescent↗
PubMed1977

Echocardiographic spectrum of mitral valve motion in children with and without mitral valve prolapse: the nature of false positive diagnosis.

To examine problems in echocardiographic diagnosis of mitral valve prolapse, multiple crystal cross-sectional echocardiography and single crystal recordings derived from the multiple crystal array were used to study 45 clinically normal children aged 3 to 15 years (Group A), 26 children aged 2 to 10 years with known mitral valve prolapse (Group B), 12 children with a catheterization-proved large left to right shunt at the ventricular level (Group C) and 8 children with catheterization-proved left ventricular outflow tract obstruction (Group D). Children in Groups A and B were not studied hemodynamically. Children in Groups C and D had no evidence of mitral valve prolapse on angiography and were studied echocardiographically to determine the effect of changes in ventricular shape on the patterns of mitral valve motion. In the real time cross-sectional studies, normal patients demonstrated a spectrum of mitral valve motion in which the bodies of the anterior and posterior leaflets became slightly horizontal with systolic ejection. The mitral apparatus assumed a curvilinear funnel shape. Arching of the leaflets into a horizontal configuration was more striking in the presence of either left ventricular dilatation in left to right shunt or involvement of the anterior mitral anulus in subaortic stenosis (two patients) and was associated with false positive M mode tracings suggesting mitral valve prolapse. This latter configuration was easily differentiated from the superior motion of the body of the leaflets in true prolapse. Studies of single crystal M mode recordings derived form the cross-sectional array in known locations from six normal patients revealed M mode patterns of pseudoprolapse in tracings derived from the leaflet body and patterns of normal motion at the free edge. In contrast, superior-posterior prolapse visualized in cross-sectional studies in patients with the click-murmur syndrome was associated with abnormal M mode recordings from all parts of the leaflet, including the free edge, although the abnormalities were most striking in tracings derived from the leaflet body. The M mode echocardiographic findings of mitral valve prolapse in both normal patients and patients with the click-murmur syndrome were dependent upon transducer angulation and the portion of the valve examined. The critical differentiation of the spectrum of normal valve motion from prolapse requires careful evaluation of echoes from the free edge of the leaflet where the posterior and anterior leaflet echoes coapt in early systole.

Adolescent↗
PubMed1977

A quantitative echocardiographic study of champion childhood swimmers.

An echocardiographic evaluation of 77 members of a championship childhood swim team showed dimensional variations from normal in most athletes. Cardiac walls were thicker than the 95th percentile of normal: right ventricular anterior wall exceeded the 95th percentile in 100%, interventricular septum in 83% and left ventricular posterior wall in 91%. The left ventricular and left atrial cavities in diastole had mean values at the 50th percentile of normal but showed considerable scatter. The left ventricular cavity in systole had a mean value less than the 5th percentile of normal and also showed wide scatter. The aortic root and the aortic intercusp dimension exceeded the 95th percentile of normal in most subjects, 74% and 77%, respectively. No correlation existed between the coach's estimate of championship ability and echocardiographic wall or chamber sizes. Children who participate extensively in athletic training programs such as swimming may have echocardiograms which are quantitatively different from those of nonathletic younsters.

Adolescent↗
PubMed1977

Suprasternal notch echocardiography. Assessment of its clinical utility in pediatric cardiology.

Echocardiographic suprasternal relationships of the transverse aortic arch (TAA), right pulmonary artery (RPA) and left atrium (Y' LAD) were validated and angiographic-echocardiographic measurement correlations were made for each structure. Normal values were determined with respect to body surface area. In normals, regardless of age or body size, mean dimensional TAA/RPA ratio was 1.2:1 and Y' LAD equaled the anterior-posterior, or Z axis, left atrial dimension (Z LAD)- TAA/RPA ratio was increased in aortic stenosis and tetralogy of Fallot and was decreased in ventricular septal defect, atrial septal defect and pulmonary stenosis. Ratio did not correlate with lesions severity as assessed by cardiac catheterization except in pulmonary stenosis. Discrepant Y' LAD values (usually increased Y' LAD and decreased Z LAD) occurred in children with various forms of heart disease. Some had sternal compression but others had normal chests. Children with pectus excavatum showed similar compression. These findings underscore the need for incorporation of a suprasternal examination into the standard echocardiographic examination of children.

Adolescent↗
PubMed1977

Real-time cross-sectional echocardiographic diagnosis of coarctation of the aorta: a prospective study of echocardiographic-angiographic correlations.

Real-time cross-sectional echocardiographic sector scan examinations were performed from a suprasternal notch location to image aortic anatomy in 15 children (ages 1 day to 21 years) who were subsequently shown at cardiac catheterization to have coarctation of the descending thoracic aorta. The resulting echocardiographic images of the ascending, transverse and descending aorta imaged juxtaductal coarctation in all 15 patients. Echocardiography predicted discrete coarctation of the aorta in eight, isthmic hypoplasia in two, hourglass type coarctation deformities in three and longer segment coarctation in four patients. Catheterization and angiography confirmed all of these anatomic observations. The control group, 100 patients with congenital heart disease but without angiographic coarctations, included four patients with right-sided aortic arch and six patients with dextrocardia. The ascending, transverse and descending aorta were adequately imaged in 94 of these and no descending aortic abnormalities were noted. This study shows the potential utility of cross-sectional echocardiography for the noninvasive precatheterization or preoperative assessment of coarctation of the aorta in children and critically ill newborns.

Adolescent↗