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Biomedical subjects

D J Roberts

Publications and source records attributed to D J Roberts.

At least 181 records · Page 10Linked to original sources

The effects of intracerebroventricularly administered noradnamine and other sympathomimetic amines upon leptazol convulsions in mice.

1. The influence of some intracerebroventricularly administered sympathomimetic amines on leptazol-induced convulsions has been investigated.2. Noradnamine and high doses of dopamine proved to be anticonvulsant and also antagonized the facilitative effects of reserpine.3. Noradrenaline and octopamine also antagonized reserpine-induced facilitation but were without effect on leptazol alone; by contrast tyramine and small doses of dopamine lowered the threshold for leptazol convulsions.4. A possible interpretation of these results is presented.

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