New amino acids from Streptomyces.
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Biomedical subjects
Publications and source records attributed to D J Mason.
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OBJECTIVE: To examine the relationships between objectively measured activity patterns over 6 months after coronary artery bypass surgery (CABS) and their relationship to self-reported functional recovery at 6 weeks and 6 months after CABS. DESIGN: Time series, descriptive-correlational, convenience sample. SETTING: Hospital and home environment. PATIENTS: Thirteen women who had undergone CABS. The mean age was 62 years (SD 10.76, range, 43 to 78). The mean preoperative New York Heart Association Functional Classification was 2.08 (SD 1.26, range, 1 to 4). MEASURES: Wrist-worn accelerometers and the Sickness Impact Profile (SIP). INTERVENTION: Women wore the accelerometers for 4 week-long intervals: the first postoperative week (T1), the first week after hospitalization (T2), the sixth postoperative week (T3), and the first week of the sixth postoperative month (T4). The SIP was administered at the end of each week of data collection. RESULTS: Circadian rhythms and linear trends in activity were examined with spectral, cosinor, and least squares regression analyses. Repeated measures ANOVA over T1 through T4 demonstrated statistically significant increases in the strength of the circadian rhythms and means levels of activity over T1 to T4. There were no statistically significant relationships between activity parameters at T1, T3, or T4 and SIP scores at T3 or T4. CONCLUSIONS: This study is the first to report changes in circadian rhythms and levels of objectively measured activity over 6 months after CABS. The findings suggest that women's levels of activity and the strength of the circadian rhythm of activity increase between the early postoperative period and the sixth postoperative month. More research is needed to further explore the trajectory of activity patterns after CABS, their relationships to recovery and to determine the need for and effectiveness of interventions designed to promote recovery through activity patterning.
A recent resurgence of tuberculosis (TB) has been driven mostly by the HIV epidemic. The initial inpatient experience for individuals with HIV-related TB may be pivotal to the acceptance of and participation in ongoing TB care. The purpose of this study was to develop an understanding of the experience of respiratory isolation for HIV-infected patients with TB in order to identify strategies for enhancing quality of life and participation in care. Respondents (N = 18) identified 12 major themes related to the isolation and reported more mood disturbances during their confinement than the norm. This study suggests that staff behaviors which foster human connections may enhance the patient's quality of life and promote adherence to therapy.
The aim of this study was to identify the best method for determining when to safely discharge the endoscopy patient; specifically, it was designed to determine whether the patient's risk factors, intraoperative occurrences, and/or medications used during endoscopy should be used to determine the minimum length of stay postconscious sedation or whether a general policy can be used, as is currently practiced at many institutions. Preoperative, intraoperative, and postoperative data were collected on a convenience sample of 405 adult ambulatory outpatients undergoing upper endoscopy and/or colonoscopy. Subjects were also interviewed by phone within 48 hours of discharge to assess postdischarge complications and their duration. Age predicted length of time in recovery, but only 2% of the variation in recovery time was predicted by the study variables. Intraprocedure occurrences predicted postprocedure occurrence. The implications of these and other findings are discussed in relation to nursing practice and future research.
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Teaching rounds can be a highly interactive, fluid process for developing staff nurses' critical thinking, assessment, and interpersonal skills. In this article, the authors describe how to conduct and evaluate teaching rounds using the example of Pain Management Teaching Rounds conducted by an advanced practice nurse on medical-surgical units of a large medical center. Qualitative and quantitative outcomes of the pain management rounds are discussed.