Determination of marker chromium in faeces using inductively coupled plasma emission spectrometry.
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Biomedical subjects
Publications and source records attributed to D J Lyons.
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Percutaneous fine-needle aspiration biopsy (PNAB) of mediastinal masses was carried out in 116 patients. The technique yielded a high percentage of correct diagnoses, and the results were usually available within hours. More importantly, the procedure was well tolerated by patients, and in this series of 116 cases, only one serious complication was encountered. There was a high accuracy (90.3%) in the cytologic diagnosis of mediastinal metastases from lung and extrathoracic sites. Excellent results were also achieved with the cytologic diagnosis of thymoma (82.4%). Very good results were achieved with benign mediastinal cysts, and PNAB with aspiration of fluid proved to be a valuable tool in the diagnosis of these lesions. The results achieved with the cytologic diagnosis of lymphoma supported by pathology (66.7%) and with neurogenic tumors were acceptable, but less impressive.
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An inductively coupled plasma spectrometric method is described for the determination of 4 elements (Ca, B, P, and Mg) in calcium borogluconate veterinary medicines. Samples are diluted, acidified, and sprayed directly into the plasma. Reproducibility relative confidence intervals for a single sample assay are +/- 1.4% (calcium), +/- 1.8% (boron), +/- 2.6% (phosphorus), and +/- 1.4% (magnesium). The total element concentrations for each of 4 elements compared favorably with concentrations determined by alternative methods. Formulation estimates of levels of calcium gluconate, boric acid, phosphorus, and magnesium salts can be made from the analytical data.
We report two cases of choriocarcinoma, one uterine, the other a component of an ovarian germ cell tumour, in both instances clinically overt thyrotoxicosis was a feature of their initial presentation. These cases highlight a rare clinical association which is due a thyrotropic action of Human Chorionic Gonadotrophin.