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Biomedical subjects

D J Hogan

Publications and source records attributed to D J Hogan.

At least 55 records · Page 3Linked to original sources
PubMed1990

The prognosis of contact dermatitis.

This article reviews the prognosis of contact dermatitis, particularly of occupational contact dermatitis. Most studies document a poor prognosis for occupational and nonoccupational contact dermatitis. The prognoses of occupational and nonoccupational contact dermatitis, irritant contact dermatitis, and allergic contact dermatitis are similar. Only a minority of studies on the prognosis of occupational contact dermatitis have found that a job change by the affected worker leads to clearing of the dermatitis. Dermatologic and nondermatologic factors associated with a poor prognosis are discussed.

Chronic Disease↗
PubMed1990

Risk factors for squamous cell carcinoma of the skin in Saskatchewan, Canada.

Completed questionnaires regarding suspected risk factors for skin cancer were completed by 178 cases of SCC of the skin in Saskatchewan, Canada, and 284 age- sex- and location-matched controls. Significant risk factors identified using chi2 analyses were: farming, family history of skin cancer, light eye color, blond or red hair color, skin types I or II, obvious freckles in childhood, history of severe sunburn, and the use of the herbicide 2,4-Dichlorophenoxy acetic acid. The following relative risks were identified: (1) All cases of SCC of the skin and matched controls: agricultural occupation 1.49, history of severe sunburn 1.49. (2) All men with SCC of the skin and matched controls: history of severe sunburn 1.36 (3) All women with SCC of the skin and matched controls: agricultural occupation 1.83, and skin types I or II 1.48. No association was noted on our study between a history of psoriasis and development of SCC. Neither was an association between smoking and SCC found.

Carcinoma, Squamous Cell↗
PubMed1990

A psychosocial assessment of patients with basal cell carcinoma.

We performed a controlled study to investigate the psychosocial problems of patients diagnosed and treated for basal cell carcinoma (BCC) as compared to the general population. Thirty-nine BCC patients and 39 matched controls answered a psychosocial questionnaire. Chi square analysis of the questionnaire results revealed no statistically significant difference between the BCC patients and the control group. In conclusion, no more psychosocial problems were found in BCC patients than in members of the general population.

Adaptation, Psychological↗
PubMed1990

Allergic contact dermatitis to ethylenediamine. A continuing problem.

Ethylenediamine would be an infrequent sensitizer if it were not present in a widely prescribed topical corticosteroid preparation that is applied to inflamed skin. Occupational allergic contact dermatitis to ethylenediamine is not common. The educational efforts of American dermatologists such as Dr. Alex Fisher have helped lead to the deletion of ethylenediamine from Mycolog cream. It is unfortunate that the same pharmaceutical company continues to use ethylenediamine in its products in other countries, as the continued popularity of these creams may allow ethylenediamine to remain a common sensitizer in some areas, particularly where inflammatory skin conditions are treated predominantly by nondermatologists.

Cross Reactions↗
PubMed1990

Review of contact dermatitis for non-dermatologists.

Contact dermatitis is common. Occupational contact dermatitis is one of the commonest occupational diseases. Allergic contact dermatitis to topical medications is frequent. This article provides an update on the two main types of contact dermatitis: irritant and allergic. The role of patch testing in evaluating patients is discussed and guidelines for treatment are given. Clinical features, prognosis, risk factors, and prevention are discussed.

Dermatitis, Contact↗
PubMed1990

Contact dermatitis: prognosis, risk factors, and rehabilitation.

This article reviews the prognosis for irritant and allergic contact dermatitis and occupational and nonoccupational contact dermatitis. Factors adversely affecting prognosis are discussed. Rehabilitation of the patient with disabling contact dermatitis is considered. The importance of the various risk factors for contact dermatitis are reviewed.

Dermatitis, Contact↗
PubMed1990

Treatment of actinic prurigo with intermittent short-course topical 0.05% clobetasol 17-propionate. A preliminary report.

Actinic prurigo is a chronic familial photodermatosis that occurs mostly in Amerindians. Eight patients with actinic prurigo were given intermittent 3- to 14-day courses of topical 0.05% clobetasol 17-propionate cream or ointment in 1988 and 1989. Seven out of eight patients cleared or markedly improved. All of the patients had been resistant previously to milder topical corticosteroids. There have been no side effects. This therapy offers an effective alternative to systemic corticosteroids, oral psoralen with long-wave UV radiation in the A range, or thalidomide.

Administration, Topical↗
PubMed1989

Risk factors for basal cell carcinoma.

Completed questionnaires regarding suspected risk factors for basal cell carcinoma (BCC) were completed by 538 basal cell carcinoma patients and 738 age-, sex-, and location-matched controls in Saskatchewan. Significant risk factors were identified using chi2 analyses. Relative risks were subsequently computed. The following relative risks were identified: occupation of farming, 1.29; prominent freckles in childhood, 1.23; family history of skin cancer, 1.22; sunburn, 1.19; Irish, Scottish, Welsh mother, 1.19; light skin color, 1.18; red/blond hair color, 1.16; and working outdoors more than 3 hours/day in winter, 1.13: The average age of cases of BCC with a family history of skin cancer was significantly lower than cases of BCC with no family history of skin cancer (63.86 vs. 67.02 years, p = 0.018). No association was noted between BCC and psoriasis.

Adult↗
PubMed1989

Patch testing in actinic prurigo.

42 out of 93 Saskatchewan Indians (32 female (F) and 10 male (M] with actinic prurigo were patch tested to standard series allergens between 1983 and 1987. Positive reactions were most frequently seen with nickel (3F:2M) and colophony. All 3 positive patch tests to colophony were in males. The same patients were also patch tested to extracts of 21 Saskatchewan plants and 3 Hollister-Stier plant extracts. Only 1 male and 2 females had positive patch tests. None of these 3 had rashes on the eyelids, behind the ears or under the chin. We conclude that plant contact dermatitis is unlikely to be mistaken for actinic prurigo in Saskatchewan.

Adolescent↗
PubMed1988

Isotretinoin therapy for acne: a population-based study.

The use of isotretinoin over a 2-year period was retrospectively studied in Saskatchewan. The database of the Saskatchewan Prescription Drug Plan was used to obtain the names of physicians who prescribed isotretinoin as well as the names of patients for whom it was prescribed. Of the 861 such patients 161 had been instructed to use the drug for at least 4 months by 42 physicians. Questionnaires were returned by 86 of the 161 patients and 22 of the 42 physicians. The responses confirmed that isotretinoin therapy is highly effective for acne. However, at least half of the patients for whom the agent was prescribed apparently did not complete a full 4- to 5-month course of treatment, and of the 34 women (average age 28 years) who responded to the questionnaire 12 (35%) did not use a method of contraception, which is a matter of concern in view of isotretinoin's teratogenic effects.

Acne Vulgaris↗
PubMed1988

Diphencyprone.

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Adolescent↗