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Biomedical subjects

D J Harris

Publications and source records attributed to D J Harris.

At least 127 records · Page 7Linked to original sources
PubMed1978

Hemangiopericytoma of the spinal canal. Report of three cases.

Hemangiopericytoma is a vascular neoplasm consisting of capillaries outlined by an intact basement membrane that separates the endothelial cells of the capillaries from the spindle-shaped tumor cells in the extravascular area. These neoplasms are found in soft tissues but have rarely been shown to involve the spinal canal. This is a report of three such cases. Surgical removal of the tumor from the spinal canal was technically difficult. A high risk of recurrence has been reported but in these three cases adjunctive radiotherapy appeared to be of benefit in controlling the progression of the disease. These cases, added to the six cases in the literature, confirm the existence of hemangiopericytoma involving the vertebral column with extension into the spinal canal. This entity should be included in the differential diagnosis of lesions of the spinal canal. The risk of intraoperative hemorrhage should be anticipated.

Adult↗
PubMed1978

An ivory vertebra: monostotic Paget's disease of bone.

The roentgenographic scintographic and histologic features of an "ivory vertebra" are characteristic of monostotic Paget's disease. This case and condition are of special interest because Paget's disease is quite unusual in persons aged 30 or younger.

Adult↗
PubMed1977

The course of the cerebrocostomandibular syndrome.

Three children with the cerebrocostomandibular syndrome have been studied. They were from unrelated families. The sib of one of them may demonstrate partial expression of a disorder that varies in severity, so that long-term survival is possible. Long-term survival may be complicated by restrictive pulmonanry disease and cardiac failure. A disorder of cellular growth may account for the symptoms.

Abnormalities, Multiple↗
PubMed1976

Antibiotic treatment of parturient women colonized with group B streptococci.

A prospective study was conducted among third-trimester parturient women with cervical or urethral colonization with group B streptococci to determine the influence of antibiotic treatment on subsequent colonizations among their infants. Cultures were obtained from dry swabs inoculated directly onto selective blood agar media containing neomycin and naladixic acid. Seventy-four women were found to be colonized among 1,098 cultured (7%). A significant reduction in colonization was noted among mothers treated with ampicillin within three weeks of completion of therapy. This difference was no longer apparent at delivery. There was likewise no difference in the colonization rate of infants in the treatment and no-treatment groups. The data suggest that additional measures must be undertaken to prevent maternal recolonization.

Ampicillin↗
PubMed1976

Confirmation of trisomy 22 by trypsin-giemsa staining.

A small-for-dates male infant with mental retardation, microcephaly, malformed ears, preauricular sinuses, epicanthal folds, micrognathia, congenital heart diseases, micropenis, and micropolygyria of the parietal and occipital lobes of the cerebral cortex was shown to have a 47,XY,+22 karyotype by trypsin-giemsa banding. Review of reported cases confirms that there may be distinctive trisomy 22 syndrome.

Azure Stains↗
PubMed1975

Familial presacral teratomas.

A tumor complex consisting of presacral teratoma and sacral deformity was described along with its occurrence in 6 kindreds. In addition to the tumor and the sacral defect, some patients have had recurrent abscesses, rectal stenosis and skin dimples as manifestation of the tumor. Urinary tract anomalies have also been found to be associated in some patients. The tumor differed considerably from the usual sacrococcygeal teratoma. Only one of the 19 resected tumors had proved to be malignant, although 2 have recurred in a benign manner. This appears to be inherited as a dominant characteristic.

Adolescent↗