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D J Doyle

Publications and source records attributed to D J Doyle.

140 records · Page 8Linked to original sources
PubMedDate not supplied

An algorithm for drug waste reduction using pharmacokinetic principles.

When delivering several intravenous drug doses from a single bag, it is generally necessary to throw away any drug that remains in the bag, if the amount is insufficient to deliver the next dose. An algorithm has been developed to allow all of the drug in a bag to be used. Based on standard pharmacokinetic equations, the algorithm calculates the time when the remainder should be given, so that a desired peak serum drug concentration is achieved on the next dose. The algorithm requires as inputs the time limit on the bag, the dosing interval and the size of the dose. This algorithm applies only to drugs that obey single compartment, first-order linear kinetics (e.g. aminoglycosides), but is easily modified for other situations. In conjunction with computer-assisted infusion, use of the algorithm may potentially reduce the cost of aminoglycoside administration by reducing clinical drug waste.

Algorithms↗
PubMedDate not supplied

A handheld microcomputer system for control of a jet ventilator.

High-frequency jet ventilation is a relatively new mode of patient ventilation that has seen application in critically ill patients with respiratory failure. Because of the radically different nature of this modality of ventilation, clinicians often are unsure which ventilator parameter settings are appropriate. The authors describe in this paper a handheld microcomputer system to assist in the control of jet ventilators.

Algorithms↗
PubMedDate not supplied

Medical computing over the World Wide Web: use of forms and CGI scripts for constructing medical algorithm Web pages.

The development of the World Wide Web has led to an explosion of educational and clinical resources available via the Internet with minimal effort or special training. However, most of these Web pages contain only static information; few offer dynamic information shaped around clinical or laboratory test findings. In this report we show how this goal can be achieved with the design and construction of Medical Algorithm Web Pages (MAWP). Specifically, using Internet technologies known as forms and CGI scripts we demonstrate how one can implement medical algorithms remotely over the Internet's World Wide Web. To use a MAWP, one enters the URL for the site and then enters information according to the instructions presented there, usually by entering numbers and other information into fields displayed on screen. When all the data is entered, the user clicks on the SUBMIT icon, resulting in a new Web page being constructed "on-the-fly" containing diagnostic calculations and other information pertinent to the patient's clinical management. Four sample applications are presented in detail to illustrate the concept of a Medical Algorithm Web page: Computation of the alveolar-arterial oxygen tension difference using the alveolar gas equation; Computation of renal creatinine clearance; drug infusion calculation (micrograms/kilogram/minute); Computation of the renal failure index.

Algorithms↗
PubMedDate not supplied

The Internet and medicine: past, present, and future.

The enormous growth of the Internet and the World Wide Web has made these two technologies an important potential adjunct to cost-effective health care research and delivery. This article surveys some recent developments in telecommunications, networking and artificial intelligence that are likely to have a significant impact on improving the efficiency and quality of future health care. Issues discussed include: clinical record keeping on the Internet, Internet-assisted medical diagnosis, privacy and security matters, financial transactions, digital money, bandwidth concerns, multimedia (music, audio and video) information delivery via the Internet, intellectual property, and the concept of Information Philanthropy.

Clinical Medicine↗
PubMedDate not supplied

Development of an academic Internet resource.

Networked electronic publication is a relatively new development that has already begun to change the way in which medical information is exchanged. Electronic publications can present ideas that would be impossible in printed text, using multimedia components such as sound and movies. Physicians who use the World Wide Web (WWW) on a regular basis may recognize the value of electronic publication and decide to become information providers. Nearly anyone with a computer and modem can create a WWW resource on a Web server at a hospital or on a commercial hosting service. Medical publication on the Internet demands a high level of quality control because the information will be available to anyone who cares to look. Creating a peer-review system for electronic information may, therefore, help to enhance academic recognition of Internet medical resources. Resources containing medical information must be continually available and protected from system failures and unauthorized access. As Internet technology matures and these problems are solved, electronic publication may become the predominant method of communication between medical professionals.

Academic Medical Centers↗