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Biomedical subjects

D J Barnes

Publications and source records attributed to D J Barnes.

53 records · Page 3Linked to original sources
PubMed1987

Haemophilus influenzae pneumonia in Melanesian adults: report of 15 cases.

In a prospective study of 170 adult patients with acute pneumonia, Haemophilus influenzae was found to be the aetiological agent in 15 cases (8.8%). The diagnosis in all cases was based on positive cultures of blood or percutaneous lung aspirate, or both. Chronic lung disease was significantly more common in patients with H influenzae pneumonia than in patients with pneumonia due to other organisms but age, sex, and smoking history did not differ significantly. Lobar consolidation was the most common radiological pattern, being present in 10 of the 15 cases. Type b was the commonest serotype isolated, but three cases were due to non-typable (non-capsulate) strains. All patients survived, responding well to treatment with penicillin, ampicillin, or chloramphenicol. Haemophilus influenzae should be considered as a possible cause of pneumonia in adults, particularly those with underlying chronic lung disease.

Acute Disease↗
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Animal models.

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Depression↗
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Community-acquired acinetobacter pneumonia in adults in Papua New Guinea.

Acinetobacter calcoaceticus, an aerobic gram-negative coccobacillus, is a rare cause of community-acquired pneumonia. It most commonly causes nosocomial infections, particularly in elderly debilitated patients who have undergone surgery, instrumentation, and antibiotic therapy. In a study of acute pneumonia in adults, five cases of community-acquired acinetobacter pneumonia were observed over an 11-month period. Other than chronic pulmonary disease (two patients), no serious underlying diseases existed in these patients. Lobar consolidation was the predominant radiologic pattern. The mortality rate was 40%, and mortality was directly related to therapy with inappropriate antibiotics. The reason for this relatively high prevalence of community-acquired acinetobacter pneumonia in the population studied is not known. Possible explanations include the high prevalence of chronic pulmonary disease, indiscriminate use of penicillin, and an unknown immunodeficiency state.

Acinetobacter Infections↗
PubMedDate not supplied

A displacement orientation program. Effects on transferred nurses.

When nursing administrators make a decision to close nursing units and displace staff nurses, nursing staff respond with feelings of anger and demoralization. Instituting a Displacement Orientation Program (DOP) can positively affect the staff nurses' level of anger, independence, innovation, self-confidence, and productivity. This article presents a research based DOP used to minimize staff reactions and maximize staff adjustments to displacement.

Employment↗
PubMedDate not supplied

Hypothyroidism in the elderly: clinical assessment versus routine screening.

A total of 304 patients aged 65 years or over were prospectively studied over a four-month period to assess whether clinical findings or routine screening were more helpful in diagnosing biochemical hypothyroidism. The most useful symptom relevant to a possible diagnosis of hypothyroidism in the elderly was found to be dry skin. Dermatological signs and certain ECG abnormalities (especially atrial fibrillation) were helpful when querying a diagnosis of hypothyroidism. Almost 50% of patients receiving amiodarone had abnormal thyroid function tests (TFTs). Routine screening for hypothyroidism does not seem justifiable from our available data although this conclusion may have been different had hospital clinicians and general practitioners followed their patients up more closely after an initial abnormal result was obtained.

Aged↗