PTERIDINE STUDIES. XXIX. THE METHYLATION OF 7-AMINO- AND 4,7,DIAMINO-PTERIDINE.
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Biomedical subjects
Publications and source records attributed to D J BROWN.
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Tautomeric forms of 2-hydroxypurine, in which the structure has been fixed by introduction of an N-methyl group, are oxidized differently by xanthine oxidase. The 1-methyl derivative is attacked at position 8 and the 3-methyl derivative at carbon atom 6. These observations indicate that 2-hydroxypurine itself reacts in a tautomeric form, corresponding to the structure of its 1-methyl derivative.
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