[Possibilities of the evaluation of autonomic regulation of cardiac activity in patients with ischemic heart disease using non-invasive methods of examination].
Vegetative control of the heart was assessed on the basis of cardiac rhythm (CR) and stroke volume parameters in the course of an active orthostatic test and bicycle ergometry in 508 myocardial infarction patients and 30 normal subjects. Central hemodynamic parameters and CR spectrum were examined with respect to phases of sleep in 125 coronary patients and 25 normal subjects. Coronary patients showed a disrupted vegetative CR regulation, which was chiefly parasympathetic (reduced CR response to an active orthostatic position and rationed exercise, and a smaller share of high-frequency constituent of the CR energy spectrum). Disrupted vegetative CR regulation was correlated with low hemodynamic baseline and respective values in active orthostatic position, exercise and REM sleep. Reduced CR response to stress as well as reduced CR spectrum during sleep corresponded to more severe clinical conditions.