Establishment of new mouse and human pigmented melanoma lines in tissue culture.
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Biomedical subjects
Publications and source records attributed to D Horn.
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We investigate the formation of a Hebbian cell assembly of spiking neurons, using a temporal synaptic learning curve that is based on recent experimental findings. It includes potentiation for short time delays between pre- and post-synaptic neuronal spiking, and depression for spiking events occurring in the reverse order. The coupling between the dynamics of synaptic learning and that of neuronal activation leads to interesting results. One possible mode of activity is distributed synchrony, implying spontaneous division of the Hebbian cell assembly into groups, or subassemblies, of cells that fire in a cyclic manner. The behavior of distributed synchrony is investigated both by simulations and by analytic calculations of the resulting synaptic distributions.
A two-phase quality assurance monitor was performed with a pediatric outpatient population to determine how well the current preparation of Fleet Phospho-Soda, Fleet enemas, and diet modification cleaned the colon. We studied 99 patients in Phase 1, implemented changes, and then studied 99 patients in Phase 2. Phase 2 found increasing age to be significantly related to decreasing cleanliness of the transverse colon, ascending colon, and cecum, and increasing weight was found to be significantly related to decreasing cleanliness of the cecum. Phase 2 also found the second enema to be significant for increasing cleanliness of the rectum.