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Biomedical subjects
Publications and source records attributed to D Hill.
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The effect of human chorionic gonadotropin (HCG) hormone on restoration of physiological continuity of the spinal cord in rats was studied. After complete transection of the spinal cord at the midthoracic level eleven of these 21 rats in the study received HCG for six weeks. The other ten served as controls. At the end of six weeks amplitude of the cortically evoked motor At the end of six weeks amplitude of the cortically evoked motor action potential (CEMAP) was measured. The amplitude of the motor action potentials was significantly greater (P less than 0.02) in HCG treated rats. The study thus shows that HCG might help in the restoration of spinal cord function.
Acute renal failure developed in a patient who received 56 grams of vancomycin intravenously over a 10 day period. The resulting serum vancomycin level was 284 micrograms per ml and declined to 140 micrograms per ml in a linear fashion with the institution of continuous arteriovenous hemofiltration (CAVH). Our conclusion is that high blood vancomycin levels may be nephrotoxic and CAVH may be an effective means of vancomycin removal in patients with acute renal failure.
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