Inversion of the uterus is a rare but dangerous postpartal complication. Morbidity and Mortality depend to a significant degree on early diagnosis and treatment. When the condition is detected early manual reposition and simultaneous shock therapy, which are usually possible, are of prime importance. Antibiotic prophylaxis should always be instituted in order to prevent any upward spread of infection. With appropriate obstetric management subsequent births can be uncomplicated, as in the case described by the authors.

Adult↗

PubMedDate not supplied

Apparent stimulation of thrombopoesis with interleukin-3 (IL-3) in chemotherapy induced myelosuppression.

Two patients with advanced ovarian cancer (FIGO III C) and one patient with abdominal cancer developed severe thrombocytopenia with petechial haemorrhages after chemotherapy. These patients were treated with recombinant human interleukin-3 (rhIL-3) after multiple platelet transfusions (HLA-matched) and erythrocyte transfusions had not been effective. Increase of thrombocyte counts began three days after rhIL-3 therapy. Side effects due to rhIL-3 administration (flu-like symptoms) were moderate and could be treated effectively with paracetamol. These data support evidence for efficacy of rhIL-3 in chemotherapy-induced thrombocytopenia and may open new therapeutic perspectives.

Abdominal Neoplasms↗