Search PubMed⌕ Search

Biomedical subjects

D Hamanaka

Publications and source records attributed to D Hamanaka.

36 records · Page 2Linked to original sources
PubMed1979

[Clinical feature and calcitonin therapy on Paget's disease of bone (author's transl)].

Bone scintigraphy with 99mTc-MDP was performed on 8 patients with Paget's disease of bone. The radionuclide uptake by all the involved lesions was markedly increased, even in subclinical lesions without pain. Bone scintigraphy with 99mTc-phosphorous compounds were thought to be the most simple and sensitive technique to define the precise extent of the lesions, and to detect asymptomatic occult cases with Paget's disease. Possible A-V shunt was estimated in 3 cases by measuring the radioactivity over the lungs after the injection of 99mTc-MAA through a catheter into an artery which supplied the lesion. A-V shunt was calculated as 14.5%, 10.0% and 12.0%, respectively. An uptake study of 99mTc-MDP was attempted to quantify the effect of calcitonin treatment using a gamma camera combined with a computer. An "uptake ratio" was obtained for each lesion by dividing the count rate over the bone lesion by that over the control bone. Three cases of Paget's disease were treated with synthetic eel calcitonin analogue ([Asu1,7] E-CT) in a dose of 40 MRC unit per day. The effectiveness of CT therapy was evaluated by the X-ray film, the serum alkaline phosphatase activity (S-Al-P), the serum phosphate level, the serum calcium level and the "uptake ratio". No remarkable changes were obtained on bone X-ray films at one year after the initiation of the CT treatment in all cases. The S-Al-P levels did not show significant difference in the 2 cases, in which the S-Al-P levels were within the normal range before the treatment. In all cases, however, the "uptake ratio" of the diseased bone fell remarkably within the first three months and the rate of the fall was parallel to the decrease in the bone pain. It was considered that the "uptake ratio" on bone scintigraphy offered the most sensitive and reliable information in evaluating the CT treatment for Paget's disease.

Aged↗
PubMed1978

[An evaluation of inhalation and perfusion scintigraphy with 81mKr (author's transl)].

As 81mKr is a radioactive noble gas which has a very short half-life of 13 seconds, it leads no environmental contamination in a laboratory room. Because of its low radiation dose in the human body, it had many merits in routine tests of the inhalation and perfusion scintigraphy, which were very useful extremely in infants, old men and severe patients in need of cooperation. The studies with 81mKr were, either, useful as a load test, since these could repeatedly readily, evaluate the ventilation and perfusion dynamics before and after administration of drugs and show the distribution of the ventilation and perfusion correspond to the various lung volume level.

Aged↗
PubMedDate not supplied

Computed tomography and angiogram of primary hepatic rhabdomyosarcoma: report of two adult cases.

Two adult cases of primary hepatic rhabdomyosarcoma, one of which was associated with hepatocellular carcinoma and had double malignant tumors, are described with emphasis on the radiologic features. On precontrast computed tomography, the lesion appeared as a well-defined hypodense mass like an abscess, while linear mottled enhancement was observed on the postcontrast scan. Angiography revealed displacement of the hepatic arteries and portal veins, irregular neovascularity in the peripheral portion, and scant tumor stain without dilatation of the feeding artery. Review of the literature revealed only 10 previous reports.

Aged↗
PubMedDate not supplied

Perinephric xanthogranulomatous pyelonephritis simulating a renal or retroperitoneal tumor on X-ray CT and angiography.

A case of perinephric xanthogranulomatous pyelonephritis is presented. Ultrasonography and X-ray computed tomography (X-CT) showed a mass on the posterior aspect of the right kidney, causing us to suspect right renal cell carcinoma. Pyelography showed a deformity of the right renal calyces. From angiographic results, we considered the possibility of hypovascular renal cell carcinoma, subcapsular tumor, or retroperitoneal tumor. The mass was diagnosed pathologically as perinephric xanthogranulomatous pyelonephritis.

Angiography↗
PubMedDate not supplied

Mycotic aneurysm.

Mycotic aneurysms must be diagnosed rapidly because of the high mortality, associated with them. X-ray computed tomography (X-CT) is a noninvasive modality. Intravenous digital subtraction angiography (IVDSA) is also much less invasive and less dangerous than arteriography, especially in mycotic aneurysms, whose wall is thin. We describe two patients with mycotic aneurysms diagnosed by X-CT and IVDSA.

Aged↗
PubMedDate not supplied

Comparison of image quality and portal vein visualization in IADSP using iopamidol, 76% urografin, and 38% urografin.

The image quality of intra-arterial digital subtraction portography (IADSP) was studied in 50 randomly assigned patients using one of three contrast agents: iopamidol, (IOP, 20 cases), 76% Na-meglumine diatrizoate (76% UG, 20 cases), and 38% Na-meglumine diatrizoate (38% UG, 10 cases). Sharpness and contrast of images, and portal vein visualization were evaluated in these groups. IOP provided better image quality and portal vein visualization than 76% UG. There was no significant difference between them in terms of side effects, such as contrast medium-induced pain and feeling of warmth, or changes in physiological parameters like blood pressure and heart rate. When a low osmolar contrast agent like IOP passes through the mesentery capillary bed, the eflux of the contrast agent into the interstitial space and the influx of water into the capillary may be less, resulting in less dilution of the contrast agent in the superior mesenteric vein. This might explain the better image quality and portal vein visualization of IOP.

Diatrizoate Meglumine↗
PubMedDate not supplied

Two cases of primary isolated chylopericardium diagnosed by oral administration of 131I-triolein.

Two cases of isolated chylopericardium, one idiopathic and the other secondary to the lymphangioma of the pericardium are reported here. In both cases, correct diagnosis was made by radionuclide imaging techniques. When imaging the cardiac pool using 99mTc-in vivo, labeled RBC, a large separation between the heart and surrounding organs was demonstrated; this suggested a presence of massive pericardial effusion. On pericardial imaging taken 24 hours after oral administration of 131I-triolein, a donut-like shape was clearly produced, situated in a gap between the separation, suggesting chylous effusion within the pericardial space. On operating, isolated chylopericardium was confirmed in both cases. To our knowledge, this is the first report of preoperative noninvasive diagnosis of chylopericardium in Japan.

Administration, Oral↗
PubMedDate not supplied

A study of regional cerebral blood flow and hemodynamics in cerebrovascular diseases by selective continuous infusion of Kr-81m.

A tomographic study of regional cerebral blood flow and hemodynamics was performed on 25 patients with cerebrovascular diseases by selective continuous infusion of krypton-81m (Kr-81m). Kr-81m single photon emission computed tomograms were superimposed on X-ray computed tomograms to assess topographically the perfusion of the entire brain. Study of cerebrovascular diseases using this method showed: (1) regional cerebral blood flow change; (2) perfusion distribution change; (3) the route by which blood reached the brain or the obstructed artery proximal to the circle of Willis; (4) development of a collateral system and its actual function; and (5) efficacy of surgical bypass after extracranial-intracranial anastomosis. This method is especially useful in hemodynamic assessment in patients with ischemic cerebrovascular disease.

Adult↗
PubMedDate not supplied

Sonographic diagnosis of biliary ascariasis.

Real-time sonographic imaging can clearly represent the biliary ascarid as a longitudinal double linear echo. We call this representation an intraductal tubular image. Such imaging allows easy differentiation of the biliary parasite from calcification and other foreign bodies in the biliary tracts.

Ascariasis↗