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Biomedical subjects

D H Rice

Publications and source records attributed to D H Rice.

At least 145 records · Page 8Linked to original sources
PubMed1976

Anomalies of the first branchial cleft.

Eleven cases of first branchial cleft duplication anomalies are classified into types I and II. Type I defects are associated with the first cleft and are duplication anomalies of the membranous external auditory canal. Type II defects are associated with the first cleft and first and second arches, and, as such, are associated with defects of the membranous external auditory canal and cartilaginous elements. Microscopical examination of tissue in type I anomalies shows a cyst lined by skin without adnexal structures and without cartilage. Type II anomalies usually contain all elements. Misdiagnosis, infection, and recurrences are common with these lesions. Clinically, they may drain through the neck and external auditory canal. Surgical excision must be complete or there will be recurrence. The facial nerve must be identified and protected during the excision.

Adolescent↗
PubMed1976

Olfactory neuroblastomas: a clinicopathologic study.

Clinical and pathologic findings in seven patients with olfactory neuroblastomas are reviewed. Thes neoplasms occurred over a wide age range and, regardless of microscopic pattern, had an unpredictable clinical course. Total extirpation followed by radiation provided optimal therapeutic benefit. The difficulty of pathologic diagnosis of olfactory neuroblastomas is emphasized by the number of neoplasms excluded from this series after critical review of clinical and microscopic findings.

Adenocarcinoma↗
PubMed1976

Neuro-otologic manifestations of sarcoidosis.

Sarcoidosis is an idiopathic disease which presents in anatomic areas of concern to otorhinolaryngologists. It can cause dysfunction of both auditory and vestibular systems. In patients known previously to have sarcoidosis, this disease should be seriously considered. In patients presenting with otologic disorders and associated facial nerve paralysis or other neuropathies, uveitis, granulomatous meningitis or diabetes insipidus, sarcoidosis should be suspected. An examination of the eyes as well as a chest X-ray is imperative. Sudden and fluctuating neurosensory hearing loss has been reported. There is a great need for the study of temporal bones from sarcoidosis patients.

Adult↗
PubMed1976

Angiosarcoma of the maxillary sinus: report of case.

The third reported case of primary angiosarcoma of the paranasal sinuses is presented. The neoplasm occured in the left maxillary sinus of a 26-year-old white woman. The patient was treated with external irradiation with cobalt of a total dose of 7,000 rads. No evidence of recurrence has been reported.

Adult↗
PubMed1975

Central perforations-safe or unsafe?

An analysis of 227 consecutive tympanomastoldectomies was undertaken to compare the types and degree of middle ear pathologic features that are found behind central perforations as compared with attic or marginal perforations. In this series, little difference was found between the two groups. A great deal of disease occurred behind all types of tympanic membrane perforations. Near-normal audiogram results did not guarantee a normal middle ear. Central perforations are not necessarily safe and should be treated with the same caution as attic or marginal perforations.

Cholesteatoma↗
PubMed1975

Sclerosing cervicitis: homologue of sclerosing retroperitonitis and mediastinitis.

The first known case of an invasive, sclerosing fibrosis of the deep soft tissue of the neck is presented. The morbidity, clinical course, and, most importantly, pathological identity with sclerosing retroperitonitis and sclerosing mediastinitis led us to consider this lesion as the cervical homologue of these lesions, ie, sclerosing cervicitis.

Carotid Arteries↗
PubMed1975

Malignancy and the benign lymphoepithelial lesion.

The benign lymphoepithelial lesion of salivary glands is now considered the histological hallmark of a variety of clinical and pathological disorders affecting salivary tissues. Malignancy arising in the lesion is uncommon, but may take origin in either the epithelial or lymphoreticular components. Lymphomas and pseudolymphomas associated with salivary gland lymphoepithelial lesions have been predominately extra-salivary and strongly correlated with Sjögren's syndrome. Epithelial malignancy has not been associated with autoimmunity and with few exceptions has been of the anaplastic type. This report presents two patients with intra-salivary lymphomas arising in a benign lymphoepithelial lesion of salivary glands and a patient with anaplastic carcinoma arising in the epithelial islands of the lesion. The fourth patient manifested pseudolymphomatous lymphoreticular hyperplasia in lung and submandibular gland and illustrates the possible multiple organ involvement that may occur in patients with benign lymphoepithelial lesion, even without clinical evidence of concommitant autoimmune disorders.

Aged↗
PubMed1975

Laryngeal carcinoma: stomal recurrences and distant metastases.

Stomal recurrence and distant metastases are two of the most serious complications occurring in the patient treated for carcinoma of the larynx. Their appearances are ominous prognostic signs for survival of the host and both are refractory to any form of effective management. To date, the stomal recurrence has defied a satisfactory pathogenetic explanation but neoplastic cell inculation of the laryngectomy wound and extension from paratracheal lymph nodes appear to be partial explanations. Uncontrolled local disease plays a significant, if not the major role in the genesis of distant metastases.

Humans↗
PubMedDate not supplied

Recurrent squamous cell carcinoma of the true vocal cord.

None of the consultants disagree with the initial plan to treat this T1N0 squamous cell carcinoma of the true vocal cord with radiotherapy. The consensus is that 10% to 20% of these lesions can fail conventional treatment. Dr. Rice cites incorrect radiotherapy ports, understaging, and extension into muscle or cartilage as the likely reasons for failure. He also believes that a patient who continues to smoke is at risk for persistent or recurrent disease. Drs. Wetmore and Singer add that some tumors are radioresistant for indefinable reasons. Although all the consultants agree that the differentiation between severe atypia and carcinoma in situ can be very difficult, Dr. Singer warns that the surgeon should not play a role in the histologic decision-making. He does not make a distinction between the two and suggests treating a lesion on the basis of its clinical behavior. Dr. Rice draws the line at treating T3 glottic carcinomas with radiotherapy. He states that the greater the tumor bulk the less well the lesion will do with radiotherapy. All the experts caution that involvement of cartilage at the anterior commissure and arytenoid is also a reason for failure. Dr. Wetmore adds that subglottic extension and verrucous carcinoma also contribute to radiotherapy failure. The real controversy lay with how to proceed in this case. Dr. Rice suggests excision of the lesion with the laser or microsurgical stripping. If the margins were positive he would proceed with a vertical hemilaryngectomy. Dr. Wetmore would excise the lesion with a CO2 laser and would follow the patient closely thereafter. He would only plan a hemilaryngectomy if the lesion recurred again.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMedDate not supplied

The pathology of head and neck tumors: squamous and mucous-gland carcinomas of the nasal cavity, paranasal sinuses, and larynx, part 6.

Carcinomas of the nasal cavity and paranasal sinuses are statistically dominated by squamous-cell lesions, which account for between 85% and 90% of the epithelial malignancies in these sites. Neoplasms of glandular derivation are far less frequent, accounting for between 4% and 8% of carcinomas in this region. Both classes of malignancy, however, indicate an ominous prognosis for their hosts, and for both, it is the extent of the cancer, and hence the clinical stage, that is the major determinant. The clinicopathologic characteristics of squamous-cell and glandular carcinomas of the nasal cavity and paranasal sinuses are presented, and for the latter, a review of their presentation in the larynx is also offered.

Adenocarcinoma↗
PubMedDate not supplied

The pathology of head and neck tumors: neoplasms of cartilage, bone, and the notochord, part 7.

Neoplasms of the supporting tissues in the head and neck are outnumbered by their histologic counterparts in the trunk and extremities. This is especially true for tumors of bone, cartilage, and the remnants of the notochord. Malignancies occurring in all three tissues, however, are just as lethal as those sited elsewhere. Chondrosarcomas and osteogenic sarcomas of the facial bones are resistant to all conventional modes of therapy, manifest many recurrences, and have an often protracted morbidity. The craniocervical chordoma manifests a similar biologic course. For the tumors of cartilaginous origin and the osteogenic sarcomas, the initial surgical attempt at removal is of key importance. Neoplasms present at the margins of resection have a poor prognosis. Chorodomas are not likely to be cured by any modality.

Bone Neoplasms↗
PubMedDate not supplied

The pathology of head and neck tumors: fibroadipose tissue and skeletal muscle, Part 8.

Benign and malignant tumors originating from mesenchymal cells destined to become lipoblasts and myoblasts affect the head and neck with contrasting frequencies. Lipomas and especially liposarcomas are unusual lesions above the clavicles but when found there behave in a biologic manner identical to that of their counter-parts at other anatomic sites. Myogenic tumors, on the other hand, have a predilection for the head and neck, and for rhabdomyosarcomas this predilection is accentuated in childhood. Combination therapy of rhabdomyosarcomas has obviated radical surgery as a method of treatment, and many sites in the head and neck have benefited prognostically by this treatment. Success, however, is dependent on clinical stage of disease, and rhabdomyosarcomas of the nasopharynx, paranasal sinuses, and middle ear remain more resistant to short-term cures because of the extent of the neoplasm. A review of the clinicopathologic aspects of granular-cell tumors and alveolar soft-part sarcomas is also presented because it has been suggested that these tumors have a myogenous origin.

Adult↗
PubMedDate not supplied

The pathology of head and neck tumors: vasoformative tumors, part 9A.

Tumors originating from components of the vascular system vary widely in the degree of morbidity and mortality that they incur. They all have endothelial cells as integral components of their histologic appearance. Vasoformative tumors include hemangiomas, lymphangiomas, and pyogenic granulomas, which are relatively common, and hemangiopericytomas, glomus tumors, and angiosarcomas, which are relatively uncommon. For many vasoformative tumors, including lymphogenous lesions, the head and neck is an area of predilection, and, in some instances, location in the head and neck appears to modify biologic activity.

Head and Neck Neoplasms↗
PubMedDate not supplied

The pathology of head and neck tumors: vasoformative tumors, part 9B.

There are three principal malignant vasoformative tumors that can be found in the head and neck--hemangiopericytoma, angiosarcoma, and Kaposi's sarcoma. All are uncommon and provide challenges for the pathologist and the therapist both. The histogenesis of each tumor is different. Kaposi's sarcoma has many features which suggest that it is an altered immune-response disease. Angiosarcoma is a malignancy of endothelium. Hemangiopericytoma is a tumor whose cell of origin is considered to be the perithelial pericyte. The general prognosis for patients with Kaposi's sarcoma is good. The biologic course of a hemangiopericytoma is variable and unpredictable, but there appears to be a site dependency. Angiosarcomas, particularly high grade lesions, are resistant to therapy.

Arteriovenous Fistula↗
PubMedDate not supplied

The pathology of head and neck tumors: carcinoma of the nasopharynx, Part 11.

The past decade has witnessed extraordinary advances in the epidemiology, virology, and immunology of carcinomas of the nasopharynx. There has not been a parallel growth in the study of morphologic expressions of the neoplasms. In great part, this has been due to a lack of a universally accepted histologic classification. As a consequence, correlation between histology and other factors relating to the pathogenesis of these neoplasms has been impeded. The World Health Organization (WHO) has proposed a histologic classification of nasopharyngeal carcinomas as squamous-cell, nonkeratinizing, and undifferentiated. This report presents and argument in favor of using the WHO classification and a hypothesis relating to the histogenesis of the 3 types of nasopharyngeal carcinoma.

Adolescent↗
PubMedDate not supplied

The pathology of head and neck tumors: mucosal melanomas, part 13.

Pigmented lesions, including melanomas, of the mucous membranes of the head and neck are far outnumbered by their counterparts in the skin. This relative dearth is partially responsible for the fact that scientific inquiry into mucosal melanomas has not kept pace with the advances in knowledge of the pathogenesis of cutaneous melanomas and their diagnosis and treatment. Integral to these latter advances have been the refinements in clinical and histologic classification and clinicopathologic correlations with quantitative evaluation of melanomas of skin-enhancements that up to now have been singularly lacking for mucosal melanomas. This report acknowledges this slowness in progress, present recommendations for purifying the nomenclature of pigmented lesions of the mucosae, and at the same time, also notes the poorer prognosis for melanomas of the upper aerodigestive tracts, as a group, when compared with cutaneous melanomas. Only prospective studies will answer the question of whether the poor prognosis is intrinsic to these mucosal melanomas or whether delay in detection and removal are responsible.

Dental Amalgam↗