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Biomedical subjects

D H Kennedy

Publications and source records attributed to D H Kennedy.

46 records · Page 3Linked to original sources

Neurological involvement in legionellosis.

A study of the clinical, electrophysiological and biochemical features of 16 patients with legionellosis has been performed. Evidence of central and peripheral nervous system involvement has been found in the majority of patients. This is characterised by confusion out of keeping with the degree of toxic or metabolic upset, signs of anterior midline cerebellar dysfunction, grossly elevated creatinine kinase of skeletal muscle origin, and a subclinical peripheral neuropathy.

Adult↗

Tuberculous meningitis.

To evaluate modern treatment and identify important factors influencing the outcome of tuberculous meningitis, clinical and laboratory findings in 52 patients aged from 9 months to 68 years have been reviewed. Patients were classified by clinical criterions at admission and at the start of treatment. Delay in commencing treatment was associated with deterioration and consequently poorer prognosis, but some severely ill patients made a good recovery. Forty-four survivors (85%) recovered, and only two patients (4%) had severe residual disability; eight (15%) of the patients died. Treatment should commence as soon as possible on clinical grounds without necessarily waiting for demonstration of Mycobacterium tuberculosis, as the organism can often be demonstrated in CSF withdrawn after the start of drug therapy.

Adolescent↗

Aetiology and epidemiology of viral croup in Glasgow, 1966-72.

A retrospective study of 258 children admitted to Ruchill Hospital, Glasgow, with croup between 1966 and 1972 indicated that the viruses most frequently associated with the syndrome were parainfluenza types 1 and 3 and influenza A. Most cases were admitted in the late autumn and winter months, with a small peak in May and June. This seasonal distribution mirrored the circulation of the main causative agents in the community, parainfluenza 1 being principally associated with the autumn cases, influenza A the winter cases and parainfluenza 3 the summer cases. Two of these ;croup associated' viruses showed regular periodicity, parainfluenza 1 occurring biennially in even years and influenza A in most years. The periodicity of parainfluenza 3 is as yet undetermined.

Adenoviridae↗

An outbreak of infantile gastroenteritis due to E. coli 0142.

Twelve cases of gastroenteritis caused by Escherichia coli 0142K86H6 are described. Ten of these cases were clearly involved in an outbreak of cross infection. The other two cases yielded interesting information on infection with E. coli. 0142. Five cases, two being fatal, required repeated intravenous infusion, and one further infant required parenteral replacement therapy on a single occasion only. Cross infection occurred at the primary site-a ward partitioned into cubicles-despite full barrier nursing techniques. Infection spread also to two other wards, and resulted from transfer of latently infected cases. Illness in several infants was protracted and debilitating because of the relapsing nature of the infection. The pathology of the two fatalities is reported briefly.

Cross Infection↗

AIDS and medical ethics.

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Acquired Immunodeficiency Syndrome↗