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Biomedical subjects

D H Buss

Publications and source records attributed to D H Buss.

At least 55 records · Page 3Linked to original sources
PubMed1984

Marked elliptocytosis and schistocytosis in hematopoietic dysplasia.

A 78-year-old white male patient presented with anemia characterized by marked elliptocytosis and schistocytosis. Other morphologic findings in the peripheral blood and marrow were diagnostic of hematopoietic dysplasia (preleukemic syndrome). Five years previously elliptocytosis and schistocytosis were not present, and the only features suggesting hematopoietic dysplasia were significant numbers of micromegakaryocytes in the marrow and rare giant platelets with giant granules in the peripheral blood. The features of this case suggest that acquired marked elliptocytosis and schistocytosis may be an unusual manifestation of hematopoietic dysplasia.

Aged↗
PubMed1984

The risk of improperly staging Hodgkin's disease with partial splenectomy.

Partial splenectomy has been proposed for staging Hodgkin's disease, but the risk of thereby missing limited splenic involvement is unknown. To assess that risk, we reviewed all spleens removed during staging laparotomies for Hodgkin's disease at our institution, assessing splenic weight, the characteristics of all nodules, and grossly visible subcapsular disease. Among 180 spleens, 65 had splenic disease. Fifty-three had six or more nodules; for 49 of those, other abdominal involvement had been present or the disease was so diffuse that staging by partial splenectomy would have been correct. The remaining 12 spleens (18%) contained five or fewer nodules. Eleven had no grossly visible subcapsular nodules, and five of the 11 were associated with no other abdominal involvement. In four of those five, the disease was localized to one area in such a way that it could have been missed by partial splenectomy. All positive spleens averaged 415 g; the four spleens with localized involvement averaged 287 g. Thus, in four of 65 patients, a few splenic nodules in a localized distribution not visible grossly were the only evidence of abdominal Hodgkin's disease, and if partial splenectomy had been done there would have been a 6.2 per cent risk of understaging their Hodgkin's disease.

Hodgkin Disease↗
PubMed1984

Folic acid content of the diet in various types of British household.

The total folic acid content of household diets in Britain has been derived from National Food Survey records for 1979, 1980 and 1981, and was found to average 210-213 micrograms/person/day. There were only small regional differences, with the South East of England and East Anglia having higher and Scotland having lower intakes than the average. Income differences were more marked, with households depending on unearned income having the highest intakes. The largest differences were found between households of different compositions groups: households without children obtained between 215 and 257 micrograms/person/day but those containing six or more people averaged only between 168 and 194 micrograms/person/day.

Adult↗
PubMed1983

Reorganization of the British total diet study for monitoring food constituents from 1981.

A total diet study was developed in the UK in the 1960s to enable the estimation of average intakes of different food constituents of public interest. Since that time the organization of the total diet study has twice been modified, firstly in 1975 and more extensively in 1981. The study now includes 115 foods in 20 groups compared to 68 foods in nine groups in the previous design, and reflects more recent food consumption patterns. The food is purchased in preselected parts of the country by a market research company and the preparation of the diets has been centralized in one laboratory instead of being undertaken by domestic science colleges located in many areas. The reorganization is described and the new total diet study is validated by comparison with a study of the previous design.

Diet Surveys↗
PubMed1983

Individual fatty acids in the British household food supply.

The amounts of some 40 fatty acids in British foods, derived from food tables and from a major new analytical survey, have been applied to National Food Survey results to give the average intake of each fatty acid in 1981. The major sources of the more significant fatty acids are also discussed.

Diet Surveys↗
PubMed1982

Chronic relapsing polyneuropathy associated with immunoblastic lymphadenopathy.

Two episodes of severe, relapsing sensorimotor polyneuropathy closely paralleled the course of systemic illness in a patient with immunoblastic lymphadenopathy. A review of the literature shows three other cases, although none with documented pathologic changes in muscles and nerves. Based on the pathologic findings in this patient, the peripheral neuropathy associated with immunoblastic lymphadenopathy can be classified under the group of relapsing inflammatory polyneuropathies associated with systemic disorders. Whether prednisone therapy helped this condition is uncertain.

Adult↗
PubMed1982

Trace nutrients. 4. Iodine in British food.

1. The amounts of iodine in nationally representative samples of prepared and cooked groups of foods and in a wide variety of individual foods and food products were determined colorimetrically. The amounts of erythrosine, a red food colour containing 577 mg I/g were also determined in selected foods and diets by high-performance liquid chromatography. 2. The average British diet was calculated to provide 323 micrograms I/d but only 255 micrograms if two fruit samples containing large amounts of glacé cherries were discounted. Of the total, 92 micrograms was derived from liquid milk. Meat and meat products provided 36 micrograms and cereal products 31 micrograms, but fresh fruits and sugars, vegetables and beverages provided little I. Fish and fish products, though rich in I, contributed only 5% to the total intake. 3. Milk was the most variable as well as the most important individual source of I. Summer milk samples contained 70 micrograms/kg and winter milk 370 micrograms/kg on average. Milk products, including butter and cheese, and eggs were also rich in I. 4. Some processed foods contained erythrosine, particularly glacé cherries and some pink or red confectionery items, biscuits, cherry cake, canned strawberries and luncheon meat. However, none of these are major foods in the average household diet and erythrosine would therefore contribute little more than 10 micrograms I/d to most diets. 5. The average daily intake of I was lower than in similar similar studies in the USA, but was twice the provisional UK recommended intake. This study provides no evidence that I intakes in the UK could be too low or too high for health.U

Diet↗
PubMed1982

Biotin, pantothenic acid and vitamin E in the British household food supply.

Intakes of biotin, pantothenic acid and vitamin E in Britain were calculated by applying values from the 4th edition of McCance and Widdowson's The composition of foods or other published values to the amounts of food recorded in the National Food Survey of 1979. National average intakes were found to be biotin distributions could also be made to the intake of the B vitamins by alcoholic drinking and confectionery. Comparison of intakes with suggested recommended intakes values were rather low while for pantothenic acid the recommendations were met.

Biotin↗
PubMed1980

Malignant lymphoma of the thyroid gland with plasma cell differentiation (plasmacytoma).

An unusual case of malignant lymphoma of the thyroid is reported. The predominant appearance of the neoplasm was that of a large cell ("histiocytic") lymphoma, but a discrete portion of the tumor showed features typical of plasmacytoma. Electron microscopy revealed a wide spectrum of cell types, ranging from very immature lymphoid cells to relatively well-developed plasma cells. The findings support the concept that the neoplastic process represents an immunoblastic sarcoma composed of proliferating transformed B lymphocytes (immunoblasts) and their progeny (plasma cells) rather than two distinct lymphoid neoplasms occurring simultaneously.

Aged↗
PubMed1980

Visceral herpesvirus infections in leukemic patients receiving cytarabine.

Autopsy evidence of herpesvirus infection was found in visceral organs of four leukemic patients who had received large doses of cytarabine (cytosine arabinoside; Ara-C) shortly before their death. In three of these patients the infection was clinically unsuspected; in the fourth, cutaneous herpes zoster developed after administration of 300 mg of cytarabine daily for the preceding five days. Although cytarabine exhibits pronounced in vitro virucidal activity against herpes viruses and has been successfully used in clinical treatment of severe herpesvirus infections, the present findings and a review of the recent literature cast doubt on the antiviral effectiveness of this drug, particularly in already immunosuppressed patients, and suggest instead that such patients actually have an increased risk for development of disseminated herpesvirus infection owing to further depression of host defenses by the drug.

Adult↗
PubMed1980

Household food wastage in Britain.

1. The total food and drink available for human consumption in the United Kingdom would provide approximately 13 MJ (3100 kcal)/person per d, while the energy intake recommended for the population is approximately 9.6 MJ (2300 kcal)/person per d. A proportion of this substantial difference must be due to wastage in the home as well as in catering establishments and during the storage, distribution and processing of food. 2. As part of a general investigation of this problem, a representative sample of 100 British households was asked to collect all the potentially-edible food wasted in their homes during 1 week, and to keep a record of the food, other than commercial pet food, which they gave to pets and wild birds. A total of 672 households co-operated fully, 338 in summer and 334 in winter. Each food sample received was weighed, and its energy content was determined calorimetrically. 3. Significantly more waste food was collected in summer than in winter, equivalent to 9.3 MJ (2220 kcal)/household per week and 7.1 MJ (1700 kcal)/household per week respectively. In terms of energy, cereals, fat and meat wastage predominated, while in terms of weight, milk was more important and fat less so. 4. Considerable quantities of otherwise edible food were also given to pets and birds, accounting on average for a further 2.4 MJ (570 kcal) and 3.0 MJ (710 kcal)/household per week in summer and winter respectively. The energy content of all food wasted in the home therefore averaged 11.7 MJ (2790 kcal)/household per week in summer and 10.1 MJ (2410 kcal)/households per week in winter, equivalent to 0.6 MJ (150 kcal) and 0.5 MJ (130 kcal)/person per d respectively. This is less than one-quarter of the gap between food supplies and the amount of food thought to be eaten in the UK. 5. Food wastage was significantly influenced by the composition of the family, with adults wasting more in absolute terms than children, and larger households wasting less per person than smaller households. However, with few exceptions, neither income nor geographical region significantly affected the total amount of food wasted in the home. 6. When assessed against the expected usage of food in the home, wastage accounted on average for 6.5% of the energy intake in summer and 5.4% in winter.

Adult↗
PubMed1980

Paraganglioma of the thyroid gland.

A case of a paraganglioma located within the thyroid gland is reported, and the light- and electron-microscopic features are described. Review of the literature reveals only one other case of intrathyroidal paraganglioma, which was associated with bilateral carotid body tumors. Regarding the present case, no similar tumors have been noted elsewhere. The findings support the view that the thyroid gland should be included among the unusual sites at which primary paragangliomas may occur.

Female↗
PubMed1980

Haem and non-haem iron in British household diets.

The amounts of haem iron, natural non-haem iron and the iron added to foods have been calculated for the average household diet and for larger families in Britain. The average intakes (/person/day) were found to be 1.3 mg haem iron and 9.7 mg non-haem iron, of which 1.1 mg were from fortification; corresponding values in families with four or more children were 0.8 mg, 8.6 mg and 1.2 mg. These lead to estimates that the amount of iron absorbed may be no higher than 0.8 mg on average and 0.6 mg/person/day in large families, or 6-7 per cent of the intake. Such values are less than those usually assumed.

Absorption↗