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Biomedical subjects

D H Brooks

Publications and source records attributed to D H Brooks.

33 records · Page 2Linked to original sources
PubMed1975

Postprandial rest pain and claudication of the lower extremity: A case report.

Postprandial rest pain and claudication in the lower extremities may occur in arteriosclerotic aortic occlusion when mesenteric and systemic collateral pathways provide inadequate blood flow to the extremity. The symptoms occur as a result of vasodilation of the distal mesenteric vascular bed with a concomitant increase in mesenteric blood flow which leads to a decrease in mesenteric artery to extremity collateral blood flow. This normal physiologic phenomenon, increase in mesenteric blood flow, causes the extremity pain. Such symptoms indicate a quite significant decrease in blood flow to the extremity, and prompt surgical correction is indicated. Aortofemoral reconstruction yields total reflief of the symptom complex.

Aortic Diseases↗
PubMedDate not supplied

Acute nonoliguric renal failure in the postoperative patient.

Fourteen patients with acute nonoliguric renal failure have been studied during the past 3 years. The mortality rate was 7% and the complication rate was 21%. Early recognition of the nonoliguric state and its maintenance with adequate volume replacement should decrease the mortality rate in postoperative acute renal failure. Reasons for the decrease in septic complications among this group of patients are not clear, but the absence of septic complications appears to be the major reason for the decreased morbidity and mortality in these patients.

Acute Kidney Injury↗
PubMedDate not supplied

An admissible solution approach to inverse electrocardiography.

The goal of the inverse problem of electrocardiography is noninvasive discrimination and characterization of normal/abnormal cardiac electrical activity from measurements of body surface potentials. Smoothing and attenuation in the torso volume conductor cause the problem to be ill posed. Standard regularized solutions employ an a priori constraint to achieve reliability and may be biased by the constraint chosen as well as the regularization parameter used to weight it. In this paper, we describe an approach that reformulates this inverse problem as the search for a solution that is a member of an admissible solution set; admissibility is defined in terms of the available constraints. In principle, this approach can utilize as many constraints as may be available, unlike standard techniques which do not easily permit the use of multiple constraints. No regularization parameter is required; instead, we need to choose the nature and size of the constraint sets. Constraints described include several spatial constraints, weighted constraints, and temporal constraints. We describe a solution approach based on iterative convex optimization, and the algorithm--the ellipsoid algorithm--which we have used. Accuracy and feasibility of the method are illustrated with simulation results using dipole sources and measured epicardial potentials.

Algorithms↗