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Biomedical subjects

D Gui

Publications and source records attributed to D Gui.

At least 19 recordsLinked to original sources
PubMed1990

[Antibiotic prophylaxis with sulbactam/ampicillin in colon surgery].

We evaluated the effectiveness of sulbactam/ampicillin (S/A) as a perioperative prophylaxis regimen in elective colic surgery (procedures lasting less than 4 hours). We studied 18 patients (11 males, 7 females; mean age 46 yrs, range 21-72), by an open, non-comparative trial: S/A was given soon before anesthesia (1 g + 2 g) and the same dose was repeated every 6 hours, up to 5 doses. The drug was well tolerated, and there were no side effects requiring the interruption of the prophylaxis. Infection rate was low (only one case of evident suppuration of the wound).

Adult↗
PubMed1990

APACHE II in surgical lung carcinoma patients.

Recent extensive development of thoracic surgery meets the need to treat elderly patients with a wide variety of pathophysiologic alterations, even if they require continuous medical assistance and high technologic support. Methods in providing such care are still limited by imprecision in evaluation of results; in this setting, a severity of disease classification system is essential to estimate the pretreatment risk of death of elder or chronically ill patients, the appropriate indication to surgical treatments, and the prediction of outcome. We tested hospital admission characteristics and hospital mortality on 59 consecutive high-risk patients from our Surgical Department using the APACHE II severity of disease classification system. Predicted mortality rate for the high-risk patients was 12.44 percent and total mortality ratio (actual deaths/predicted deaths) was 0.94. The APACHE II scoring system showed good correct classification rate, sensitivity, and specificity.

Carcinoma, Non-Small-Cell Lung↗
PubMed1989

Validation of a severity of illness score (APACHE II) in a surgical intensive care unit.

The intensive care unit is an important resource for the treatment of patients needing medical and surgical care for complicated diseases. The diversity of diseases and the difference in arrangements between hospitals providing such care have limited the precision of evaluations of intensive care. We have measured the admission characteristics and hospital mortality of 598 consecutive patients admitted to our Surgical Intensive Care Unit (SICU) using a severity of disease classification system (APACHE II) on the first day of admission. Hospital outcome details were available on 87% of the SICU patients. The overall mortality was 21.7%, mean APACHE score for survivors and non-survivors was 14.2 and 22.4, and their risk of death was 21.1% and 54.1%. The APACHE II scoring system provided an excellent means of classification, with a higher sensitivity and specificity.

Female↗
PubMed1982

Effects of supine versus sitting bedrest upon blood gas tensions, cardiac output, venous admixture and ventilation-perfusion ratio in man after upper abdominal surgery.

The effects of body position (sitting versus supine) on respiratory and haemodynamic patterns were evaluated in nine patients who have undergone upper abdominal surgery. Posture showed no significant influence upon arterial blood gas tensions, while in the sitting position mean central venous oxygen tension lowers and arterial-venous oxygen content difference rises. In seated patients cardiac output was notably reduced. Pulmonary gas exchange analysis, according to Riley's method, showed that the sitting position allows a higher alveolar ventilation-pulmonary capillaries perfusion ratio, as well as a lower degree of venous admixture.

Abdomen↗