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Biomedical subjects

D Goulian

Publications and source records attributed to D Goulian.

At least 19 recordsLinked to original sources

Further refinements on the triangular flap closure of the cleft lip.

Refinements in the triangular flap closure of the unilateral cleft lip are presented. Randall's mathematical interpretation of the Tennison repair has been extended by using a series of arcs to determine the crucial points which form the triangular flap. Using this easily taught method, an isosceles triangular flap can be plotted which will interdigitate into the noncleft side of the lip. Two symmetrical vertical distances on either side of the cleft are thus formed. This allows for a standardized repair which may be more readily taught than the rotation-advancement technique. In addition, flaps are created which are turned medically toward the cleft and are used to accentuate the philtral pout, close the nostril floor, and reinforce the lip repair, allowing closure of even extremely wide clefts in one stage. These refinements in using the triangular flap closure for the repair of the unilateral cleft lip are diagrammatically presented. We believe that these refinements enhance the results of this closure.

Cleft Lip↗

Computer use in the medical specialties.

This article summarizes new and innovative uses of the computer in various medical applications. It highlights the use of this technology in the fields of Cardiology, Radiology, Rehabilitative Medicine, Laboratory Medicine, and so on. It also discusses future uses in aiding the handicapped patient to ambulate, the deaf to hear, and the blind to see.

Artificial Limbs↗

Cleft lip: morbidity and mortality in early repair.

A fifteen-year survey of primary lip repairs done at The New York Hospital revealed that lip closure can be accomplished during the first week of life with no mortality and with major morbidity slightly higher than that in repairs done after one week of age. Modern anesthetic techniques have markedly reduced respiratory complications from lip closure. Adequate postoperative sedation coupled with careful patient monitoring should appreciably reduce the incidence of wound dehiscence.

Cleft Lip↗

Xanthoma disseminatum: an unusual cause of facial and limb deformity.

A rare case of xanthoma disseminatum producing deformity of the head, neck, and extremities is reported. This pathologically benign disease, considered to represent one of the histiocyte proliferative disorders, is manifested by numerous cutaneous xanthomas primarily in flexion areas. Progressive enlargement of these lesions accompanied by marked fibrosis has produced the severe cosmetic and functional deformities described in this patient. Treatment in this case involved excision of xanthomatous contraction bands with split-thickness skin grafting, followed by intensive physical therapy.

Arm↗

Transplantation of the cryopreserved nipple-areolar complex.

The full nipple-areolar complex of dogs has been successfully removed, cryopreserved using a controlled-rate freeze protocol, and reimplanted without loss of viability. The technique for reimplantation calls for the use of a new fixed double bolus technique that prevented dislodging or contamination in all but 2 cases. The feasibility of performing this procedure in humans is discussed.

Animals↗

Screening the nipple for involvement in breast cancer.

On the basis of independent clinical and pathological screens, mastectomy patients can be effectively classified into high-risk and low-risk groups for neoplastic involvement of the nipple-areolar complex. Clinical criteria included gross nipple signs, cutaneous signs, and tumor location, size, and bilaterality. Pathological criteria comprised subareolar involvement multicentricity, and nodal involvement. Fifty consecutive women undergoing mastectomy for cancer at the New York Hospital-Cornell University Medical Center underwent classification into high-risk and low-risk groups on the basis of these criteria. Fifty-four percent of the patients studied passed the screens and were included in the low-risk group. The incidence of nipple involvement in this group was 0. In the remaining 46%, failing either or both of the screens and constituting the high-risk group, the incidence of neoplastic involvement of the nipple was 35%. All involved nipples fell into this group.

Breast↗

The successful one-stage surgical management of a midline cleft of the lower lip, mandible, and tongue.

Developmental growth toward, and fusion at, the midline of the paired first branchial arches results in normal mandibular integrity. Failure of this process is the cause of midline mandibular clefts and associated clefts of the lower lip and anterior tongue. A case is presented with these findings, complicated by the presence of a single ventricle and transposition of the great vessels. A successful one-stage repair of the clefts of the lower lip, tongue, and mandible was performed.

Cleft Lip↗

A small tissue sample, rapid freeze-drying method for monoamine histochemistry.

A simple technique, and an inexpensive, easily assembled freeze-drying apparatus is described. This system rapidly dries small tissue samples to give good reproducible results in preparation for the histochemical visualization of monoamines, by utilization of liquid nitrogen and dry ice sublimation under vacuum.

Biopsy↗

Repair of small veins with absorbable collagen tubules.

An experimental technique is presented for the repair of very small veins using a biodegradable collagen tubule as an internal splint. The technique is simple and the long-term results are excellent. Variable patency rates in the first two weeks are being investigated.

Animals↗