Search PubMed⌕ Search

Biomedical subjects

D Goldstein

Publications and source records attributed to D Goldstein.

237 records · Page 14Linked to original sources

Eight ways to go "e" without launching a Web service.

With more than 100 million Americans on the Internet, the physician-patient relationship is evolving. The Net brings with it unlimited potential for communication and information dissemination, but these benefits do come with some side effects. No everything on the Net is reliable or credible, but many patients don't understand that. For this reason and others, physicians must involve themselves with online communication and e-commerce. There are many realistic and practical ways for physicians to do this, and not all of them involve building a Web site. Sending patients clinical information in a cost-effective manner, improving receivables management, and decreasing the volume of phone calls are just some of the many ways the Net can enhance your practice. Think of the Net as just another business tool--not a replacement for physician-patient relationships. Like the telephone before it, the Net affords improved communication, patient education, and relationship-building with patients.

Humans↗

Suppression of natural killer cell activity by hydrocortisone.

The in vitro effect of physiological levels of hydrocortisone (HC) on NK activity of human lymphocytes was investigated. Lymphocytes incubated with HC 20-80 micrograms/dl (200-800 ng/ml) prior to NK assay showed depressed NK activity similar to that previously reported at higher doses. The responsiveness of NK cells to augmentation by alpha and gamma interferon was also appreciably depressed by HC. Inhibition of cytotoxicity was not due to a toxic effect of the drug since the viability of the effector cells after incubation was comparable to control cells. Indomethacin was able to partially reverse hydrocortisone suppression in 7 out of 12 experiments. Results of these in vitro studies demonstrate that hydrocortisone, when used at the levels found in humans treated with interferon, could have significant immunomodulatory effects that would be expected to alter the immunostimulation induced by the interferons.

Cytotoxicity Tests, Immunologic↗