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Biomedical subjects

D Gogălniceanu

Publications and source records attributed to D Gogălniceanu.

At least 19 recordsLinked to original sources
PubMedDate not supplied

[Reconstructive plastic repair in cancer of the lips].

Lips neoplasm represent 20% from all maxillo-facial cancers, more than 90% being localized on the inferior lip. This paper present the results of the reconstructive surgery on 208 patients treated over 10 years (1984-1993) at the Bucco-Maxillo-Facial Surgery Clinic from Iaşi. The procedures were different according with the dimensions of the tumor and several other factors regarding there histopathological type, moment of the diagnostic, age etc.

Adult↗
PubMedDate not supplied

[Post-therapeutic complications in mandibular fractures: a retrospective study].

The analysis in based on 12,096 patients with fractures of the mandible admitted to and treated in the Clinical of Oral and Maxillofacial Surgery of Iaşi in the interval 1951-1995. Posttreatment complications were found in 10.52% of the cases, 9.81% of them being of inflammatory type. Anatomo-clinically these consisted in suppurations of the soft tissues, osteitis and osteomyelitis. The prejudices caused by these complications were multiple: longer hospital stay, additional suffering for the patient, temporary work inability, higher treatment costs.

Adult↗
PubMedDate not supplied

[The treatment of segmental fractures of the middle face].

During the past two decades new methods and techniques for the treatment of middle floor facial fractures have been developed. The orthopedic approach alone or associated with various procedures of internal suspension gradually became obsolete. Nowadays, a successful treatment implies the early surgical exploration and a careful restoration of bone skeletal structure. Osteosynthesis with mini-plates provides for the reduction and tridimensional stability of bone fragments. Moreover, in the communicative fractures and in those accompanied by substance loss, the titanium mini-plates are the best method for the immediate fixation of bone grafts.

Facial Bones↗
PubMedDate not supplied

[Method and optical device for exactly hinge axis localization tested on original phantom].

The quickly and exactly method of location of the hinge-axis is based on the moiré effect, produced between two superposed optical nets, one of it being moved. A face bow is fixed on the mandible to the occlusion rim. Two optical devices are mounted on the bottoms of the face bow. Two other optical nets are applied on the skin, corresponding to the TMJ. During the opening movements of the mandible when a pure rotation of the mandibular condiles take place on the TMJ, the optical nets are displaced and me exactly register the place corresponding to the rotation axe and we can note on the skin the hinge axis. The checkout was done using a phanthom achieved in our department, consisting of a skull made up of polyestheric resins and an elastic element made up of PVC.

Cephalometry↗
PubMedDate not supplied

[Urokinase-type plasminogen activator (uPA) and its inhibitor--new prognostic factors in oral squamous cell carcinoma].

Several cell biological studies have shown that the invasiveness of different malignant tumors (breast, renal, prostate, gastric, ovarian cancers) depends at least in part on the urokinase type plasminogen activator (uPA) and its inhibitor PAI1. uPA converts plasminogen into plasmin. Plasmin degrades tumor matrix components and starts invasion and metastasis. Our target was to see the possible prognostic relevance of the tumor-associated proteolytic factors and to compare with tumor size, nodal status and grading. Our results suggest that the invasive and metastatic potential of squamous cell carcinoma is correlated with overexpression of uPA and PAI1.

Algorithms↗
PubMedDate not supplied

[Plunging ranula].

The plunging ranula is a relatively uncommon phenomenon which represents a mucus escape reaction occurring from disruption of the sublingual salivary gland. We present a retrospective study over a 10 years period on patients suffering of plunging ranula treated in Oral and Maxillo-Facial Clinic, resumed by a clinical example. These 7 patients with plunging ranula are related to all the patients operated for ranula in the same period of time in our clinic and were analyzed on age, sex, imaging exploration technique, treatment, and outcome. We found this kind of lesion both in children and young adults, between 10 to 40 years, more frequent on male (1.33/1). Two patients presented only the cervical form of ranula instead of the other five patients (both oral and cervical ranula). Only two of them received IRM examination. All of them received surgical treatment, the approach being cervical; it was removed both the cyst and the sublingual salivary gland. The surveying period, except the last case, was 1 year and includes no recurrences. We consider, besides esthetic loss that the cervical approach of plunging ranula seems to be the optimal access both on lesion and sublingual gland.

Adolescent↗
PubMedDate not supplied

Temporomandibular joint ankylosis. A possible complication in juvenile psoriatic rheumatism.

The authors present a rare case of bilateral temporomandibular joint ankylosis secondary to polyarticular juvenile psoriatic arthritis in a 24 year-old man. The patient first presented with arthritis of his right elbow joint at the age of 9, followed by involvement of the distal inter-phalangeal joints of his right foot and both sacroiliac joints. Serum rheumatoid factor was not detected. At the age of 16 he developed psoriatic lesions affecting his nails and skin. By the age of 20, clinical and radiological evidence of arthritis was detected in his temporomandibular joint (TMJ). Subsequently, the patient developed bilateral TMJ ankylosis over a period of 4 years. The patient was managed by bilateral resection of the ankylosis bone blocks, mobilization of the mandible and interposition of Dacron material between the two neo-articular surfaces. 10 months postoperatively the patient maintained an inter-incisal distance of 3 cm. Postoperative mechano-therapy was hindered by the limited use of the patients' hands.

Adult↗
PubMedDate not supplied

[The value of radical surgical treatment in benign symmetric lipomatosis].

Benign symmetric lipomatosis (BSL) is a rare proliferative disorder of the adipose tissue, characterized by symmetrical fat deposits, predominantly in the neck and shoulder area, upper back and arms. This study contains the analyse of a lot of ten patients with BSL, which were surgical treated in our department between 1994-2004. The followed parameters were: sex, age, heredo-collateral antecedents, associated organic diseases, the motivation of medical addressability, the sites of first lesions, the length of evolution before the admission, methods for diagnosis, number of surgical sessions necessary to extirpation of fat deposits, the results of the periodic follow-up examination. The followed patients with BSL were treated by surgery (extirpation of the cervical fat masses): one surgical session (8 cases) or two sessions (2 cases). The morphological, functional and psychic results were good. Recurrence at the site of surgery was not detected in any follow-up subjects. The elective treatment in BSL is surgical, by extirpation of the lipomatous masses; a satisfactory, lasting result can be expected only after the most radical possible extirpation (not only for cosmetic intentions).

Adult↗
PubMedDate not supplied

[Surgical prosthetic restoration after bilateral maxillectomy].

In 6 cases of tumors, two gigantic benign and four malignant in T4 having palatal and gingivo-alveolar starting point with invasive evolution into the structure of facial mass, surpassing the median alignment, the authors consider the problem concerning the indications for exeresis, possibilities of removal of healthy tissue and the reconstruction of massive losses of substance. The surgical treatment of reconstruction that completes the exeresis of the tumor is meant to sustain the ocular globe through a aponeurotic-muscular flap form the temporal muscle, with the aid of nasal septum or a skin graft also used to obtain a good coating of the cavity, and is also meant to a plastic reconstruction of the soft palate as well as to retention modelling of the cavity fields which resulted postsurgically. The main role in maxillofacial reconstruction in held by the obturator prosthesis that avoids morphofunctional prejudices and restores facial contour, without aesthetic and psychic prejudices. The results obtained in our 6 cases shown here have been fully satisfactory.

Adult↗
PubMedDate not supplied

[The reconstruction of the losses of substance in the floor of the mouth with split lingual flaps].

The loses of substance, as a result of malignant tumor removement of floor of the mouth, with or without metastasis in the afferent ganglions, have such multiple and difficult morphological complications, that need immediate and complete reconstruction. From the multiple sources with reconstructive potential of the loco-regional or distant prevention suggested in literature, authors have used lingual musculo-mucosal flap. The use of the lingual flap avoided the inconveniences and the risks of tissue transfer from another origin, offering the advantages of one and only surgery and at the same time the superior morphological and functional results.

Aged↗
PubMedDate not supplied

[Infections in the oral and maxillofacial areas: their prevalence (1983-1992) and the evolution of the antibiotic sensitivity of the microbes involved].

A retrospective clinical study (1983-1992) was done in order to establish the frequency of etiological agents in determining peri-maxillary infections and also for evaluate the evolution of antibiotics resistance of isolated bacteria. The study group consisted of 5227 patients with different infections in maxillo-facial territory. Year distribution of cases was equilibrate. Study group particularities were synthetic analysed. Our results revealed the predominance of anaerobic streptococci (33.6%) and Staphylococcus aureus (32.5%) and also mixed infections (23.04). Etiological diagnosis of peri-maxillary infections was proved as an essential step for a correct treatment.

Adolescent↗