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Biomedical subjects

D Gill

Publications and source records attributed to D Gill.

At least 145 records · Page 8Linked to original sources
PubMed1969

Biradical spin labeling for nerve membranes.

We have explored the behavior of pair interaction in a suitable biradical when it is bound by van der Waals' forces in a nerve membrane. We have concomitantly examined a set of model solvents to represent this situation. It appears that the biradical suffers a restriction of internal motion with a minimal restraint on its external motion in the nerve medium. The biradical is so situated as not to respond to the passage of the action potential.

Electron Spin Resonance Spectroscopy↗
PubMed1966

The effects of acute haemorrhage on respiration in the cat.

1. The effect of haemorrhage on minute ventilation, arterial blood pH and end-tidal CO(2) has been investigated in cats anaesthetized with Nembutal. There was no change in minute ventilation with alteration of blood pressure above 100 mm Hg. Below this level ventilation progressively increased, the minute ventilation at 60 mm Hg being 33% above that at 100 mm Hg. The increase in minute ventilation was always associated with a fall in end-tidal CO(2) and a decrease in arterial blood hydrogen ion concentration.2. The effects were not influenced by vagotomy, but were abolished by carotid sinus denervation or carotid body destruction. After vagotomy and sinus denervation or aortic and carotid chemoreceptor destruction, haemorrhage resulted in a depression of respiration.3. The changes in arterial blood pH and end-tidal CO(2) did not occur without a change in minute ventilation.4. When the changes in arterial blood pH during haemorrhage were prevented by administration of CO(2) there was a marked increase in minute ventilation. It is concluded that the respiratory drive to respiration in the cat during haemorrhage is controlled mainly by carotid body chemoreceptors and that the resultant alkalaemia decreases the respiratory response.

Animals↗
PubMedDate not supplied

Testosterone levels in midtrimester maternal and fetal plasma and amniotic fluid.

Testosterone was measured in maternal plasma (58 samples), amniotic fluid (71 samples) and fetal plasma (55 samples) in 79 patients between 15 and 23 weeks' gestation. Maternal plasma testosterone levels were unrelated to fetal sex. Amniotic fluid testosterone was significantly higher in male than female fetuses but did not reliably predict fetal sex. A correct diagnosis of fetal sex was made by testosterone assay of pure fetal plasma in 39 out of 40 males and in 15 out of 15 females using 1.70 nmol/l as the cut-off value. This investigation is not the method of choice for routine fetal sexing but may be of value in fetuses suspected of having certain endocrine disorders.

Amniotic Fluid↗