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D Germain

Publications and source records attributed to D Germain.

110 records · Page 7Linked to original sources

Chronic granulocytic leukemia : early detection of metamorphosis with "in vitro" culture of granulocytic progenitors.

The study of bone marrow granulocytic precursors (GM CFU-C) has been made in patients with a chronic granulocytic leukemia (CGL), at diagnosis and during the evolution. In vitro growth was increased with a normal clusters/colonies ratio in 17 patients, 2 have presented a metamorphosis. In vitro growth was abnormal in 30 patients, 22 have presented a metamorphosis with a median of 9 months after the in vitro study. The in vitro growth of GM CFU-C in CGL patients could detect the metamorphosis.

Bone Marrow Cells↗