Louis Hector Berlioz (1803-69).
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Biomedical subjects
Publications and source records attributed to D Geraint James.
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John Coakley Lettsom (1744-1815) regarded his West Indies birthplace and the New England states as integral parts of the colonial Empire, and described himself as Americanus. He had numerous friends in the American medical profession and was generous to them with books, plants and financial support. They travelled to Europe with letters of introduction to him and some of them became corresponding members of the Medical Society of London. This work is a brief profile of some of these academic friends.
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John Coakley Lettsom (1744-1815) helped found the Medical Society of London in 1773. Its headquarters are in an elegant Regency building in central London, which contains a medical historical treasure trove. It celebrated its three hundredth session of lectures and social functions in 2003. Since 1850 the Presidency has been for one year only. In 1971 a group photograph of Presidents was arranged and a brief account of each of these distinguished men is given in the order of his seniority in the office.
John Coakley Lettsom (1744-1815), the Quaker physician, lived and worked in London but two of his daughters married brothers of the Elliot family, from Carmarthenshire. His wife was a member of the Miers family, who also had connections with Wales. This paper traces these connections.
Respiratory tract infections are a major cause of morbidity and mortality in adults and children worldwide. Because of its anatomical features, which allow gaseous exchange, the respiratory tract is constantly exposed to the outer environment and to the systemic and pulmonary circulation, which may allow infectious microbes, toxins, allergens, dust, and other antigens to enter the lung. The human host is a perpetual battleground between the body's immune system and invading antigens, whether they are microorganisms, chemicals, or cancer cells. Although a vast amount of literature is accumulating on the subject of immune responses to pathogens, the mechanisms underlying specific immunity to many organisms remain unknown. Paradoxically, while the immune response has evolved to confer protection against invading antigens, much human pathology arises when the immune responses are evoked.
Jonathan Hutchinson is a convenient starting point for a glimpse through the history and milestones of sarcoidosis. The influence of various countries is recognized by its pioneers of sarcoidosis. This historical account is brought up-to-date by the word "NOW," implying how are we addressing the enigma that continues to elude us--namely, the cause of sarcoidosis. This review of the past 150 years or so outlines the countries and personalities that have carried the Olympic torch.
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BACKGROUND: Management of splenic enlargement due to sarcoidosis consists of primarily medical therapy with prednisone, methotrexate or antimalarial drugs. Splenectomy is the last resort because of the concern about complications of surgery. AIM: This study was conducted to explore indications for splenectomy in sarcoidosis and to assess if complications associated with splenic removal were unacceptable. METHODS/RESULTS: 13 sarcoidosis patients had their spleens removed for one or more of the following four reasons: (1) Massive splenomegaly; (2) Severe hypersplenism; (3) Need for excluding lymphoma or malignancy; and (4) Precaution against splenic rupture. All patients received strict prophylactic protocol and were followed over a period ranging from 1 to 30 years. CONCLUSION: In this long term follow-up study none of the thirteen patients developed serious infections or sepsis. No deaths occurred that might be related to splenectomy.
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