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Biomedical subjects

D Gaburro

Publications and source records attributed to D Gaburro.

7 recordsLinked to original sources
PubMed1992

Surfactant-like material in the antral gastric mucosa of children.

It has been proposed that the hydrophobicity of the gastric mucosa is due to surfactant-like material (SLM), mainly composed of phospholipid, adsorbed to the mucosal surface. Biochemical and physiological studies have been performed in different mammals but morphological data on children are lacking. In the present work, the presence of SLM on the antral gastric mucosa of children has been studied by electron microscopy. The results demonstrate that SLM is present and shows two different forms, lamellar bodies and lamellar layers. In the mucosae without endoscopic, histologic, and ultrastructural alterations we have found SLM when the tannic acid method has been used but not when the tissue has been fixed only in glutaraldehyde. Our results suggest that in children with ultrastructural alterations of the epithelium, the amount of gastric SLM is increased in respect to children with a normal mucosa and that the amount of SLM on the surface of the gastric antral mucosa is modified in pathologic conditions.

Adolescent↗
PubMed1978

Unilateral cryptorchidism with compensatory hypertrophy of descended testicle in prepubertal boys.

5 prepubertal boys with unilateral cryptorchidism and compensatory hypertrophy of the descended testicle, 22 prepubertal boys with unilateral cryptorchidism and without CTH, and 14 prepubertal normal boys were submitted to LH-RH and to HCG tests in order to study the hormonal behaviour in CTH phenomenon before puberty. High but normal peaks of plasma LH and FSH were observed after LH-RH in CTH boys who showed a significant increase of testosterone after HCG stimulation. On the contrary the LH response to LH-RH and the testosterone response to HCG of the boys with unilateral cryptorchidism and without CTH were, as expected, significantly lower than in the control ones.

Child, Preschool↗
PubMed1978

A simplified method for the evaluation of human faecal flora in clinical practice.

Qualitative and quantitative evaluation of aerobic and anaerobic faecal flora was determined by a new and easy method. 10 microliter of 12 ten-fold dilutions in saline of samples of faeces were plated on the surface of culture media solidified in wells of sterile virology plexiglass plates (diameter 16 mm; 0.5 ml culture media) and incubated at 37 degrees C for 24 h. The same dilutions and the same plexiglass plates were used under anaerobic conditions for analysis of anaerobic flora (under atmosphere of N2 85%, CO2 10%, H2 5%, negative pressure, at 37 degrees C for 48 h). The analysis was performed on 35 healthy breast-fed newborn infants, 1--6 days old. After birth, the meconium in sterile; already at 25 h of life some bacterial species (Lactobacilli, Bifidobacteria, Bacteroides) show the maximal concentration in faeces and do not grow afterwards; other bacterial species (Coliforms, aerobic and anaerobic Streptococci) increase gradually during the first week of life. This method gives the same results as the conventional techniques (i.e. Petri dishes), but in an easier and quicker way; therefore it seems useful in clinical practice.

Bacteria↗
PubMed1977

Persistent post-enteritis diarrhoea.

Clinical, biochemical, and gastroenterological data have been examined im 48 patients in two age groups, one under 12 months of age, the other between 12 and 30 months with persistent post-enteritis diarrhoea. In these patients, the illness consisted of chronic diarrhoea which followed acute enteritis. It brought about a mild malabsorption syndrome with impairment of growth, particularly in infants under one year of age. Chronic inflammation with mucosal damage due to alteration of the intestinal microflora by inappropriate diets and therapy seemed to be the cause of persistent diarrhoea in these patients.

Acute Disease↗