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Biomedical subjects

D G Young

Publications and source records attributed to D G Young.

At least 109 records · Page 6Linked to original sources
PubMed1979

How much value is muscle charting? A study of the relation between neonatal assessment of muscle power and later mobility in children with spina bifida defects.

95 syrviving children with spina bifida were examined between the age of 3 to 8 years and their mobility assessed in relation to the charting of muscle power in the neonatal period. There was no good correlation between these two methods of assessment and the value of repeated muscle charting by the physiotherapists is questioned.

Child↗
PubMed1979

Current experience of neural tube defects in the West of Scotland.

The experience at the Royal Hospital for Sick Children,Glasgow, of infants admitted due to a neural tube defect has been reviewed. Two hundred and seventy-one infants were admitted in the years 1972 to 1978. In 1972 amniocentesis and in 1975 serum AFP screening were commenced in the region. Analysis of the results in Glasgow shows the latter programme to have resulted in the termination of 78% of these pregnancies complicated by the fetus having anencephaly but only 19% of those with spina bifida cystica. Spina bifida patients are a continuing medical and social challenge for which continued resources must be deployed.

Female↗
PubMed1977

Myocardial abscess complicating healed myocardial infarction.

An isolated myocardial abscess due to Bacteroides fragilis developed in the scar of a myocardial infarction. Fever, chills and signs of pericarditis were the main clinical features. Mild enteritis 1 week prior to the onset of symptoms related to the abscess was the most likely cause of the bacteremia. The diagnosis was established at thoracotomy, performed because of cardiac tamponade. Thirteen other cases of isolated bacterial myocardial abscess accompanying myocardial infarction have been reported, but all the infarctions were recent. Surgical resection for a suspected myocardial abscess should be considered in view of the high mortality, largely from cardiac rupture.

Abscess↗
PubMed1976

Ovarian tumours in childhood: a 27-year review.

Twenty-five children treated for ovarian neoplasms at the Royal Hospital for Sick Children, Yorkhill,Glasgow, between 1947 and 1974 are reported. Eight of the patients had malignant tumours and 17 benign. The patients with benign tumours were treated by either salpingo-oophorectomy or oophorectomy. The malignant cases were treated with either surgery alone or in combination with deep X-ray therapy and/or chemotherapy. Two patients died of malignant teratoma, but the remaining 6 with malignant teratoma, dysgerminoma or endodermal sinus are well. The management of these patients is discussed.

Adolescent↗
PubMed1976

Congenital laryngotracheosophageal cleft.

Two infants with complete laryngotracheoesophageal cleft are presented. One infant had hypoplasia of the left bronchus and lung and the other had a cystic dysplastic right kidney. The literature is reviewed and a scheme for managing infants with this severe and as yet lethal anomaly is presented.

Abnormalities, Multiple↗
PubMed1976

Tobramycin in pediatric use.

The new aminoglycoside antibiotic, tobramycin, was used for treatment of gram-negative and staphylococcal infection in 38 neonates, infants, and children in a pediatric surgical unit. Levels of drug in serum after administration by intramuscular, intravenous, and intraperitoneal routes were monitored, and control of infections was generally good within the therapeutic range of 2.0-10.0 mug/ml with a standard dosage regimen of approximately 5 mg/kg per day. Impairment of renal function and concurrent lincomycin therapy were important factors causing variation of levels in serum outside this range. Levels of tobramycin in cerebrospinal fluid after intraventricular instillation varied greatly in one patient, but were satisfactory in another. Clinical and bacteriological assessment of results indicated only two failures of treatment, although infection with a known resistant organism supervened in three cases. Screening for renal, hepatic, and hematological toxicity revealed only one case of transient and reversible renal impairment. Response to tobramycin therapy was generally rapid and satisfactory in a group of young patients with moderately severe infections, many of which were complicated by the presence of a congenital anomaly.

Anti-Bacterial Agents↗
PubMed1975

Subphrenic abscess in children.

Nineteen consecutive cases of subphrenic abscess which were treated in the Royal Hospital for Sick Children, Glasgow, from 1962 to 1972 are analyzed. This complication of intra-abdominal suppuration of surgery still carries a grave prognosis. Four of the patients died (21 per cent); 2 deaths were related to the subphrenic abscess while the remaining 2 were not directly related to the abscess. The mean hospital stay of the survivors was 59 days (range 30-122 days). The changing patterns of aetiology and presentation which have recently been emphasized in general surgical practice are not reflected in this paediatric series.

Ampicillin↗
PubMed1975

Bacterial colonisation and infection in lesions of the central nervous system.

A study was made of the pattern of bacterial colonisation during the first month of life in a group of 116 newborn infants with spina bifida. 55 patients subsequently developed a total of 90 infective episodes and in over three-quarters of these episodes there was a correlation between the infecting and colonising organisms. The principal sites of infection were the lesion, the ventricles and the urinary tract, and infection accounted for 27 of the 35 deaths in the series. Some of the factors governing the pattern of colonisation and the development of infection in newborn patients are discussed.

Bacterial Infections↗