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Biomedical subjects

D G Oreopoulos

Publications and source records attributed to D G Oreopoulos.

At least 289 records · Page 16Linked to original sources

Use of the Deane prosthesis in patients on long-term peritoneal dialysis.

The Deane peritoneal prosthesis has been used successfully in the treatment of 21 patients with chronic renal failure who were maintained on peritoneal dialysis for periods of up to 20 months. All patients were dialyzed for 24 hours twice weekly. While the prosthesis was still in place, transplantation was carried out in seven patients and laparotomy in three. The prosthesis was also used temporarily whenever a permanent peritoneal catheter (Tenckhoff's) failed because of infection; it was used until the signs of infection disappeared, then the permanent catheter could be replaced safely. From a total of 1136 dialyses 36 positive cultures were reported. Clinical peritonitis was found on only four occasions.

Adolescent↗

Plasma calcitonin in renal osteodystrophy.

Whether calcitonin plays a significant role in the pathogenesis of renal osteodystrophy is not known. Plasma calcitonin-like activity (CLA) was measured by means of an extraction procedure and bioassay in 17 patients with chronic renal failure. Recent bone biopsy data were available for 11 patients. Plasma CLA was found to be in the normal range in the patients studied. There was a positive and strong correlation between plasma calcium and plasma CLA. Chronic dialysis and renal transplantation had no significant effect on plasma CLA. The severity and type of bone lesions did not correlate with plasma CLA. Although plasma calcitonin in chronic renal failure does not appear to be directly related to renal osteodystrophy, normal mobilization of calcitonin may protect the skeleton to some degree from the high levels of parathyroid hormone usually present in such patients.

Adult↗

Diquat poisoning.

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Adolescent↗