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Biomedical subjects

D G Moyes

Publications and source records attributed to D G Moyes.

At least 55 records · Page 3Linked to original sources
PubMed1980

Valveless anaesthetic circuits incorporating scavenging.

A new principle is described which eliminates the need for expiratory valves in anaesthetic circuits. Scavenging of waste anaesthetic gases is also achieved. The innovations are simple, allow easy cleaning and sterilization, and can be regarded as disposable if necessary. The advantages of low circuit pressure and ease of operation are described.

Anesthesia, Endotracheal↗
PubMed1980

Effects of low concentrations of nitrous oxide on rat fetuses.

The long-term inhalation of air polluted with nitrous oxide has been implicated in spontaneous abortions and fetal abnormalities in operating room personnel. Studies with 1% and 0.5% N2O in air have confirmed the adverse effects of dilute concentrations of N2O in pregnant rats. The present study was designed to determine the threshold concentration of nitrous oxide necessary to produce adverse responses in pregnant rats. Wistar albino rats were mated in an environmental chamber and conception confirmed by vaginal smears. Immediately thereafter, the rats were randomly divided into control and experimental groups. The control rats were exposed for 19 days to oil-free compressed air in an environmental chamber at a flow rate of 8.5 air changes per hour. Experimental animals were exposed continuously under identical conditions to concentrations of 0.0, 0.1%, 0.5%, or 0.025% N2O. On day 19 the gravid rats were killed. The corpora lutea of pregnancy were counted and related to the number of fetuses in the uterus. Fetuses were fixed, cleared, and their skeletons stained with alizarin red. Litter size, frequency of fetal resorption, and fetal crown rump measurements were significantly different following exposure to 0.1% N2O than they were in control rats or in rats exposed to 0.05% or 0.025% nitrous oxide, neither of which had any fetal effects. The suggested threshold level of 30 ppm (0.03%) N2O in humans may be unrealistically low.

Abnormalities, Drug-Induced↗
PubMed1979

A comparison between meptazinol and omnopon in the relief of postoperative pain.

In a random double-blind trial, meptazinol 100 mg, a new hexahydro-azepine derivative, was found to be comparable to Omnopon (papaveretum) 20 mg when given intramuscularly for the control of pain in 50 cases after hysterectomy. The onset of analgesia was rapid and the effect lasted for about 3 hours. Cardiovascular and respiratory systems remained stable. No significant difference as regards sedation and nausea was noticed between the two groups.

Adult↗
PubMed1979

Clinical effects of nitrous oxide and oxygen mixtures at sea-level and at 1700 metres altitude.

The effects of nitrous oxide, at sea-level and at an altitude of 1700 m, were assessed on a subjective and objective basis. Only marginal differences were shown between the effects of the gas at sea-level and 1700 m. Since consciousness was impaired with 60 and 70% nitrous oxide it is suggested that the use of Entonox-oxygen mixtures should be considered for single-handed operators.

Adult↗
PubMed1978

Nitrous oxide contamination in dental surgeries using relative analgesia.

The concentrations of nitrous oxide were determined at various positions in four dental surgeries in which nitrous oxide sedation was used without scavenging. Contamination was present in all the surgeries, the greatest concentration being recorded at the dentist's nose and the least in the peripheral air. The reception area adjoining the surgeries was found also to be contaminated by nitrous oxide.

Air Pollutants↗
PubMed1975

The respiratory effects of tilidine hydrochloride.

A standard 50-mg dose of tilidine hydrochloride (Valoron) was administered to 20 patients in the postoperative phase of open-heart surgery. No significant change in respiratory status, as measured by arterial blood gas analysis, was demonstrated with this dosage.

Acid-Base Equilibrium↗