Search PubMed⌕ Search

Biomedical subjects

D G Fenwick

Publications and source records attributed to D G Fenwick.

11 recordsLinked to original sources
PubMed2002

Anaphylaxis to Haemaccel and cross reactivity to Gelofusin.

A recent change from Haemaccel to Gelofusin as the preferred colloid for resuscitation in our region caused us to review patients who were known to be allergic to Haemaccel. As Gelofusin and Haemaccel are both modified gelatine, it seemed likely that cross reactivity could occur. Two patients who had been diagnosed previously as having had anaphylactic reactions to Haemaccel were tested intradermally with dilutions of 1/100 of Haemaccel and Gelofusin. Both patients showed similar positive reactions to each agent. It appears that patients who are known to be allergic to Haemaccel are probably allergic also to Gelofusin. Both patients have been given new Medic Alert bracelets stating "Allergic to Haemaccel and Gelofusin".

Anaphylaxis↗
PubMed1984

Site of action of intravenous regional anesthesia.

The principal site of action of intravenous regional anesthesia was studied using both prilocaine HC1 0.5% and technetium pertechnetate to define their distribution in the upper limb during this method of anesthesia. Using a single upper arm tourniquet and injecting technetium pertechnetate into a cubital fossa vein, the isotope spread to the finger tips. When a double tourniquet system was used to isolate the hand from the forearm, the following results were obtained: for up to 20 min after injection of the 40 ml of normal saline and radioisotope there was no leakage into the general circulation nor into the hand; after injection of 40 ml prilocaine HCl 0.5% into a cubital fossa vein, there was no anesthesia in the hand except for a small area on the dorsum corresponding to the area of sensory distribution of the radial nerve; while the tourniquets were inflated there was cramping pain in the hand. The results indicate that the initial analgesia obtained with the intravenous regional technique was due to blockade of small nerves or possibly nerve endings and not of the major nerve trunks at the elbow as has been suggested previously.

Adult↗
PubMed1975

Management of tracheal rupture involving both bronchi.

A patient with a rupture of the lower trachea and both bronchi is presented. A review of the significant clinical findings is presented, and the anaesthetic management is discussed. The necessity of early bronchoscopy in these patients and the ready availability of experienced medical staff in assessing all severe trauma is emphasized.

Adolescent↗