Search PubMed⌕ Search

Biomedical subjects

D G Caralis

Publications and source records attributed to D G Caralis.

27 records · Page 2Linked to original sources
PubMed1978

Detection of ventricular ectopy in patients with coronary heart disease and normal subjects by exercise testing and ambulatory electrocardiography.

Maximal exercise testing and 24-hour ambulatory electrocardiographic recording (Holter monitor) were utilized in the detection of ventricular ectopy in 90 patients with stable chronic coronary heart disease and in 30 normal subjects. Although the occurrence of any ventricular ectopic activity, as detected by either or both methods, was common, the incidence was significantly higher (P less than 0.001) in patients with coronary heart disease (86 percent; 77/90), as compared to that in normal subjects (40 percent; 12/30). Ventricular arrhythmia was more frequently detected by the 24-hour continuous electrocardiographic recording, being found in 70 of the 90 patients with coronary heart disease and in ten of the 30 normal subjects. In comparison, exercise testing disclosed ventricular ectopy in 56 of the 90 patients with coronary heart disease and in two of the 30 normal subjects. Multiform and repetitive patterns of ventricular ectopy were detected twice as commonly by continuous electrocardiographic recording than with exercise testing, and these patterns were present in one-half of the patients with coronary heart disease. Both methods of examination adjunctively disclosed more ventricular ectopy than either method alone.

Angina Pectoris↗
PubMed1977

Ventricular arrhythmia 24 hours before and after maximal treadmill testing.

To determine if maximal exercise treadmill testing influences the occurence of ventricular arrhythmia in the hours after exercise, 45 myocardial infarction and 22 angina pectoris patients (New York Heart Association Class I-II), and 23 normal subjects were examined with 24-hour ambulatory electrocardiographic Holter recordings before and after exercise testing. Comparison of qualitative and quantitative ventricular arrhythmia detected during identical chronological two-, four-, and 20- or more hour periods, before and after exercise testing in each patient, revealed no statistically significant difference in any patient group. The prevalence of ventricular ectopy in 80 per cent of ischemic heart disease patients and 30 per cent of normal subjects as detected by 24-hour Holter recordings was similar to previous studies. It is concluded that in ambulatory ischemic heart disease patients (New York Heart Association Class I-II) and normal subjects, maximal treadmill testing does not significantly affect the occurrence of ventricular arrhythmia in the hours after exercise.

Angina Pectoris↗
PubMed1977

Detection of pulmonary edema in acute myocardial infarction.

To evaluate methods for detecting pulmonary edema, pulmonary extravascular water volume was measured at 24 hour intervals (total 72 hours) in 25 patients with acute myocardial infarction. Measured lung water was compared with results of clinical, blood gas, X-ray and hemodynamic methods for detecting pulmonary edema. Increased pulmonary extravascular water volume on one or more measurements was observed in 18 of the 25 patients and was associated with an abnormal chest radiograph and increased pulmonary arterial wedge, pulmonary arterial diastolic and right atrial pressures. It was associated less well with clinical, blood gas and other hemodynamic measurements. Pulmonary arterial diastolic or pulmonary wedge pressure was a significant predictor of lung water 24 hours later. Both "preclinical pulmonary edema" and the "therapeutic phase lag" could be predicted from the pulmonary wedge pressure. Clinical, blood gas, radiographic and other hemodynamic measurements were not predictive.

Acute Disease↗
PubMed1977

Serum total and free thyroxine and triiodothyronine during dynamic muscular exercise in man.

The effect of strenuous dynamic muscular exercise on serum-free thyroxine (FT4) and free triiodothyronine (FT3) concentrations has been studied in 10 healthy subjects. In the course of 7.8-19 min of treadmill exercise (protocol of R. A. Bruce), the group showed a mean increase in serum albumin concentration of 11.4% (P less than 0.01). Five subjects demonstrated an increase in FT4 concentrations (x = +54%) and five showed decreased FT4 (x = -36%). The difference in FT4 concentrations was accounted for primarily by acute alterations in dialyzable fraction T4 (DFT4) rather than total serum T4. Mean changes in DFT4 were statistically significant (P less than 0.02) when increased FT4 and decreased FT4 groups were compared. Acute exercise was accompanied by a 9% decrease in dialyzable fraction T3 (DFT3) (P less than 0.02) in the 10 subjects, but the concomitant decrease in FT3 concentration was not significant. Changes in DFT4 and DFT3 and FT4 and FT3 concentrations were not correlated. Trends in double product (heart rate times blood pressure) with maximal exercise and in double-product recovery after exercise suggested that increased FT4 concentrations developed in subjects who were physically better trained.

Adult↗
PubMed1977

Ambulatory electrocardiography. A clinical perspective.

Advances in modern technology have made it possible to record and analyze the electrocardiographic data of ambulatory persons for as many as 24 h or more. This capability and an increasing awareness of cardiac dysrhythmias and myocardial ischemia as a cause of morbidity and mortality have led to the more widespread use of ambulatory electrocardiography in the examination of patients for various clinical conditions. From a clinical viewpoint, we review and summarize the present state-of-the-art of ambulatory electrocardiography and discuss when such studies are indicated, frequently warranted, or may be useful.

Aged↗
PubMed1976

Familial sinoatrial node dysfunction. Increased vagal tone a possible aetiology.

Clinical and electrophysiological studies of a 13-year-old boy with sinus bradycardia revealed sinus node dysfunction. Long-term follow-up data of members of his family indicated familial sinus node dysfucntion. Increased vagal tone was present in all patients. It is suggested that excessive vagal discharge for a pronlonged time may be the basic mechanism of sinus node dysfunction in these patients.

Adolescent↗