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Biomedical subjects

D G Benakappa

Publications and source records attributed to D G Benakappa.

18 recordsLinked to original sources
PubMed1990

Comparative evaluation of the antipyretic efficacy of ibuprofen and paracetamol.

An open multicentric trial was conducted on 175 patients to compare the antipyretic efficacy of ibuprofen (7 mg/kg) and paracetamol (8 mg/kg). Children between the age of 4 months and 12 years with fever were admitted to the study, 85 in the ibuprofen group and 90 in the paracetamol group. The axillary temperatures were recorded at half hourly intervals for 2 hours. The mean fall in temperature at 1, 1.5 and 2 hours was similar in both groups and the differences were not statistically significant (p greater than 0.05). At half hour, the fall in temperature (mean +/- SEM) for ibuprofen was 0.1975 +/- 0.0409 and for paracetamol was 0.3843 +/- 0.0490. This absolute difference of 0.19 degrees C was statistically significant (p less than 0.05). We conclude that ibuprofen has antipyretic activity comparable to that of paracetamol and that it could be a valuable alternative antipyretic in clinical practice. There is a need to repeat this trial with higher doses of ibuprofen, to establish a dose response of the drug, if any, and to find an optimally effective dose.

Acetaminophen↗
PubMed1989

Breast-feeding practices in rural Karnataka (India) with special reference to lactation failure.

A survey was done in a remote rural area of Karnataka with a questionnaire. Overall 274 lactating mothers from a population of 10,000 were interviewed, to know the practices of breast-feeding with special reference to lactation failure. It was found that the majority of the mothers (97.09%) in rural areas breast-feed. Lactation failure is not a problem. 58.4% reject colostrum but know the advantages of breast-feeding while a small number of mothers (19.8%) start supplementary feeds by three months of age. However, 80.3% of mothers breast-feed up to 12 months. Burping (44.53%) and proper posturing (92%) of the child is not being practiced. Initiation of breast-feeding within 4-6 hours was noted only in 8.03% of mothers whereas 53.07% of mothers and 9.72% of mothers started sugar water and castor oil as prelacteal feedings respectively. It is interesting to note that grandparents (21.9%) and auxiliary nurse midwives (21.9%) are the chief influencers of breast-feeding.

Attitude↗
PubMed1987

Causes of delay in the adequate treatment of childhood illness in India.

A retrospective study of children attending a government hospital in Bangalore was performed to assess the causes of delay in providing appropriate treatment. Delay had occurred in 59% of children with significant illness, and in over half the cases the primary cause of delay was inappropriate treatment or delayed referral by a doctor trained in Western-style medicine. It is concluded that there are a large number of ill children in Bangalore whose parents are seeking the help of such doctors but where management is at fault.

Adolescent↗
PubMedDate not supplied

Management of tuberculosis.

Tuberculosis is a common disease in children but it is highly mismanaged. It is bound to be triggered off by HIV infection in the near future. The importance of HIV and TB has become apparent from the high incidence of disease caused by mycobacteria in AIDS patients. The injudicious use of needles and syringes should be discouraged in high HIV prevalence countries. Multiple drug resistant tuberculosis is emerging as one of the most important problems in medical history. It is often created by health workers who administer anti-TB drugs improperly. The diagnostic aspects and treatment are discussed.

AIDS-Related Opportunistic Infections↗
PubMedDate not supplied

Reye's syndrome in Bangalore.

One hundred and twenty four cases of Reye's syndrome admitted to Vanivilas Children's Hospital, Bangalore were investigated. Clinical, biochemical and epidemiological details were obtained. The median age was five years, with no difference in sex ratio. This disease was frequent in winter months. Cases clustered in certain congested localities of the city among lower socio economic strata. Aspirin and varicella could not be associated as preceding factors. The clinical and biochemical features of the patients were suggestive of Reye's syndrome. Histopathological evaluation was done in 104 liver biopsy specimens. Virological studies for influenza and arbovirus were negative. Mortality was high (78%).

Biopsy↗