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Biomedical subjects

D Freed

Publications and source records attributed to D Freed.

34 records · Page 2Linked to original sources

Antagonism of xylazine hydrochloride sedation in raptors by yohimbine hydrochloride.

The mean time to initial reversal response (MTIRR) and the mean time to perching (MTP) were measured in 34 raptors sedated with xylazine hydrochloride with dosages ranging from 1.0 to 20 mg/kg intravenously (i.v.) and 2.5 to 20.0 mg/kg intramuscularly (i.m.). Yohimbine hydrochloride, given i.v. (0.2 mg/kg), 30 min after the injection of the xylazine, shortened the MTIRR and MTP compared to the controls. No adverse effects were noted due to the use of yohimbine. Yohimbine appeared to be a safe and effective antagonist for xylazine sedation in raptors.

Animals↗

Direct microvascular monitoring with implantable ultrasonic Doppler probes.

A method for constructing high-frequency pulsed Doppler ultrasonic microprobes is described. Such probes were constructed and implanted on the femoral arteries of 14 rats. All of the probes gave excellent signals during the early postoperative period and all probes were found to be functional when retrieved one month after implantation. We feel that high-frequency pulsed Doppler microprobes have important advantages for microvascular monitoring.

Animals↗