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Biomedical subjects

D Franke

Publications and source records attributed to D Franke.

At least 73 records · Page 4Linked to original sources
PubMed1985

[Folic acid deficiency anemia caused by therapy in chronic renal insufficiency].

The turbidimetric determination of folic acid concentration in serum and erythrocytes was made by means of a spectrophotometer multiscan in 35 conservatively treated patients with chronic renal failure with a minimum creatine retention of 309 mumol/l and in 63 hemodialysed patients with terminal renal insufficiency. The result showed a statistically significant diminution of serum folic acid concentration in those patients treated in a conservative manner and a significant diminution of plasmatic and erythrocytic folate++ activity in patients under hemodialysis. There was a correlation between the folic acid concentration and the hemoglobin level in both groups of patients, whereas there was no correlation to the number of leukocytes and thrombocytes. A protein deficiency diet or loss of dialysis through the capillary membrane could be found to be the cause for the loss of folic acid. The possibility of folate++ substitutive therapy and its performance was discussed and recommended for selected indications.

Adult↗
PubMed1984

[Postoperative cholangiography using the T-drain canal].

Postoperative cholangiography using the T-drain canal (PCST) with flexible fibre endoscopes was done in five patients. Cases were palliative papillary drainage in malignant occlusion, passage of the intact papilla, expulsion of concrement through the cut papilla, bougienage of inflammatory bile duct stenosis with lavage removal of stone, and an endoscopic selective peripheral bile duct drainage. In one female bile duct stone wedging after endoscopic sphincterotomy of the papilla during chemical litholysis had occurred previously. For removal of residual concrements PCST competes with catheter extraction, chemolitholysis, dilatation of the papilla and endoscopic sphincterotomy. Thus far, complications are not serious. In cases of good cooperation between surgeon and endoscopist PCST could develop into a routine method.

Aged↗
PubMed1982

[Scintigraphically demonstrable bone contusions as a cause of aseptic bone necrosis].

The author refers to a group of 13 adult patients, who suffered trauma to the upper or lower extremities. Longstanding pain for weeks and months, but no positive x-ray or laboratory-findings were able to explain the complaints. Only by bone scan a constant elevated uptake was demonstrable. The author used the name "bone contusion" for this phenomenon. The scan was the most sensitive procedure to document sequels of trauma. It is recommended to use bone scan in longstanding symptomatology with negative x-ray findings after trauma and in patients who developed avascular necrosis. This may proof a relation between trauma and avascular necrosis.

Adult↗
PubMed1979

[Incidence of gestational diabetes and changes in insulin secretion of pregnant women (author's transl)].

The 50-g oGTT was applied to pregnant women suspected of having contracted diabetes. Carbohydrate tolerances were pathological in 23.6 per cent of all probands and in borderline vicinity in 17.9 per cent. The oral glucose tainting test thus worked according to expectation by revealing a relatiively high frequency of disorders of the carbohydrate tolerance. Yet, impaired insulin secretion was established rarely, with high response having been recorded from only seven per cent and delayed insulin secretion from 4.1 per cent. Low response was not found at all. No correlations were found to exist, by the 50-g oGTT, between disorders of the carbohydrate tolerance and insulin secretion. The groups involved differed but little with regard to their IRI mean value curves. Sugar excretion in urine was found to be increased with significance in response to pathological carbohydrate tolerance in early pregnancy and may be used as a complementary criterion for diagnosis.

Blood Glucose↗
PubMed1978

[Arterial involvement in elbow-proximal injuries].

Nine cases of distal brachial artery injury were discussed. We refer to case No. 7 in which a complete dorsal displacement of the artery occurred through the fracture-line of the epicondyle. Trauma caused dislocation, laceration, or spasm of the artery, with or without intravascular thrombosis. Vascular spasm should not be diagnosed unless an arteriogram is available. If not done preoperatively, it can be done during operation. In this case inspection of the vessel during operation seems essential. Venous interposition is satisfactory for bridging defects of the distal brachial artery even in the elbow region.

Adolescent↗