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Biomedical subjects

D Francis

Publications and source records attributed to D Francis.

184 records · Page 11Linked to original sources
PubMedDate not supplied

Testicular germ cell tumors. Classification based on fine needle aspiration biopsy.

Fine needle aspiration (FNA) biopsy was performed preoperatively on 13 patients with testicular germ cell tumors. The cytologic typing of the tumors was based on the presence or absence of seminoma, embryonal carcinoma, yolk-sac tumor, choriocarcinoma and teratoma in the aspirate. The cytologic findings showed good agreement with the histologic findings. Only four cases showed a single type of tumor; the other nine cases showed as many as four different tumor components. A few characteristic cytologic features proved to be sufficient for tumor typing; this suggests that FNA biopsy cytology can also be useful in identifying metastatic germ cell tumors in extra-gonadal sites.

Biopsy, Needle↗
PubMedDate not supplied

Pulmonary blastoma. Preoperative cytologic and histologic findings.

The preoperative positive cytologic and histologic findings in ten cases of pulmonary blastoma are presented and compared with the results from the literature. In eight of our ten cases a preoperative diagnosis of cancer was possible, and in six of them a review of the material disclosed a biphasic feature. A pulmonary blastoma may be suggested when the preoperative microscopic specimens show immature tumor cells of tumor tissue with biphasic differentiation.

Adenocarcinoma↗
PubMedDate not supplied

Intranuclear cytoplasmic invaginations in a Hürthle-cell carcinoma of the thyroid.

According to the literature, the finding of intranuclear cytoplasmic invaginations in fine needle aspiration biopsies from thyroid tumors is indicative of a papillary thyroid carcinoma. A case is presented in which the aspiration specimen showed marked intranuclear cytoplasmic invaginations from a tumor that histologically was a Hürthle-cell (oncocytic) carcinoma with a trabecular pattern. The classification of thyroid carcinomas and the significance of intranuclear cytoplasmic invaginations as a criterion for thyroid malignancy are discussed.

Adult↗