Search PubMed⌕ Search

Biomedical subjects

D F Merten

Publications and source records attributed to D F Merten.

At least 73 records · Page 4Linked to original sources

The sonographic diagnosis of neonatal adrenal hemorrhage.

Neonatal adrenal hemorrhage can be diagnosed with a combination of ultrasound and excretory urography without resorting to surgical exploration or invasive diagnostic procedures. The radiologic findings of adrenal hemorrhage on excretory urography include downward displacement of the kidney on the affected side and a radiolucent suprarenal mass on the body nephrogram phase. Ultrasound studies reveal a sonolucent suprarenal mass. Four cases of varying degrees of adrenal hemorrhage are presented together with the radiographic and sonographic findings.

Adrenal Gland Diseases↗

Hyperimmunoglobulinemia E syndrome: radiographic observations.

Susceptibility to recurrent staphylococcal cutaneous and respiratory infections beginning in infancy associated with extreme hyperimmunoglobulinemia E is a recently described primary immunodeficiency syndrome. Other clinical features include depressed cellular immunity and deficient antibody formation. Recurrent pneumonia and cyst formation with variable persistence and expansion characterized the radiographic couse in 11 patients. Five cysts resolved with continuous antistaphylococcal therapy; 2 were resected without recurrence; and 4 persisted after surgery and/or antibiotics (2--8 years). The cysts had dense, necrotic surfaces with fibrous walls, eosinophilic and other inflammatory cell infiltrates, and frequent, persistent, bronchial connections. Sinusitis (9/9) and mastoiditis (3/4) were also observed radiographically.

Adolescent↗

Massive congenital tricuspid insufficiency in the newborn.

Three cases of massive congenital tricuspid incompetence in the newborn are reported and discussed from diagnostic, pathologic and etiologic points of view. The diagnosis is important as cases have been reported with spontaneous resolution.

Angiocardiography↗

Atlantoaxial malformation in a 46,XY, 17q+ child.

A child with 46,XY, 17q+ chromosome aberration and unusual skeletal abnormalities had the presenting symptom of respiratory arrest after a fall and minor head trauma. He exhibited proportionate short stature, peculiar facies with antimongoloid slant, simian creases, postaxial hexadactyly, metatarsus adductus deformity, and anomalous penoscrotal configuration. Delayed speech and mild mental retardation were also present. Atlantoaxial dislocation secondary to odontoid process hypoplasia was demonstrated. Additional skeletal abnormalities included dysplastic changes in the first and fourth metacarpals, the middle phalanx of the second finger, and hypoplasia of the first metatarsal, with medial insertion of the great toe. Treatment consisted of halo jacket cast and fusion of the occiput to C1, C2, and C3. Early detection and preventive surgery for atlantoaxial dislocation is necessary to prevent neurological deficit and possibly death by respiratory failure.

Axis, Cervical Vertebra↗

Acute appendicitis in a child associated with prolonged appendiceal retention of barium (barium appendicitis).

An instance of acute appendicitis in a child associated with prolonged retention of barium by the appendix and formation of a barolith was presented. Previous reports have implicated barium in the etiology of appendicitis and suggest routine roentgenographic follow-up of all cases in which barium enters the appendix. Considering the frequency of this observation and the lack of an established relationship between prolonged retention of barium and appendicitis, this suggestion seems unwarranted.

Acute Disease↗

Renovascular hypertension as a complication of umbilical arterial catheterization.

Renovascular hypertension (RVH) in the neonatal period is frequently associated with thromboembolic complications of umbilical artery catheterization. Seven newborn infants with RVH were studied by angiography and/or radionuclide examination. Aortography and, in one case, selective angiography showed variable degrees of renal artery occlusion or attenuation. Thromboembolic defects were frequently present in other vessels. Radionuclide flow studies, renograms, and computer analysis of data (ADAC) demonstrated defects in renal function, indicative of renal ischemia. There was a high degree of correlation between angiographic and radionuclide studies. Successful medical management suggests a more conservative alternative to nephrectomy in the hypertensive newborn.

Angiography↗

Persistent fetal circulation: an evolving clinical and radiographic concept of pulmonary hypertension of the newborn.

The roentgenographic presentations of 11 newborn infants with hypoxemia secondary to pulmonary vasospasm and subsequent right-to-left shunting of blood through the foramen ovale and/or ductus arteriosus (persistent fetal circulation) are described (P. F. C. Syndrome). One infant had radiographically normal lungs, while ten had pulmonary parenchymal abnormalities including hyaline membrane disease [4], meconium aspiration syndrome [4], or an ill defined pattern of retained lung fluid [2]. The roentgenographic appearance of the lungs, however, was discordant with the severe hypoxemia observed in most. Heart size was variable but some degree of cardiomegaly was commonly present. Tolazoline, a potent vasodilator, was useful diagnostically and may have resulted in increased survival. An expanded clinical and roentgeonographic concept of the PFC syndrome is suggested.

Female↗

Computed tomography in the evaluation of herpes simplex encephalitis.

A case of newborn congenital herpes simplex type 2 viral infection is presented. Computed tomography (CT) revealed diffuse hydrocephalus, and confirmed the periventricular nature of the brain calcifications. The pathologic, radiographic, and CT findings are discussed.

Encephalitis, Arbovirus↗

Radiographic diagnosis of choanal atresia induced prenatally with triamcinolone in the baboon (Papio cynocephalus).

Choanal atresia was diagnosed radiographically using a water soluble contrast media in 2 of 7 Papio cynocephalus exposed to triamcinolone acetonide in utero. In one P. cynocephalus, the atresia was complete and was associated with other orofacial abnormalities. The other animal, previously considered to be normal, had a partial nasal obstruction. The radiographic appearance of the drug-induced defects observed in the baboon closely resemble the descriptions of spontaneously occurring defects in human infants.

Animals↗

Wilms' tumor in adolescence.

Two cases of Wilms' tumor in adolescent males are presented. The clinical and radiographic findings were unusual and both presented atypical gross and microscopic features that could be correlated with the radiographic findings. Histologic examination of both tumors showed evidence of tubular and glomerular maturation, a feature usually associated with Wilms' tumors of early infancy. One of the tumors contained a large amount of cartilage and bone. The other was grossly cystic and incorporated some features of multilocular cystadenoma, a benign metanephric tumor.

Adolescent↗

Neonatal hypoxia and pulmonary vasospasm: response to tolazoline.

Forty-six neonates with hypoxemia were treated with tolazoline, a pulmonary vasodilator, within the first two days of life. Eight of ten (80%) infants without apparent lung disease responded with a mean increase in PaO2 of 116 torr within one hour of beginning tolazoline infusions. One of the responding infants and two nonresponders died. Thirty-six additional infants with a variety of pulmonary disorders had severe hypoxemia which was refractory to mechanical ventilation. Twenty-one (58%) responded with a mean increase in PaO2 of 130 torr within one hour after beginning tolazoline and 13 (62%) of these survived. Fifteen patients had little or no improvement in PaO2 following tolazoline and only three (20%) of these infants survived. Responders could not be distinguished from nonresponders by clinical or laboratory features prior to therapy with tolazoline. Fourteen infants experienced complications possibly related to tolazoline.

Female↗