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Biomedical subjects

D Englert

Publications and source records attributed to D Englert.

3 recordsLinked to original sources

Decrease in motor activity - an early symptom in the course of experimental allergic encephalomyelitis (EAE).

Motor activity has been followed in rats during an experimental allergic encephalomyelitis (EAE). The disease was produced by transfer of lymph node cells from sensitized syngenic donors. Small and large movements were permanently registered by an electric activity meter. It could be demonstrated that a decrease of the motility is an early symptome of the disease. Therefore the measurement of the motoric activity might be a useful parameter in the classification of EAE.

Animals

Effect of increased potassium concentrations on particle motion within a neurosecretory structure.

Intensity fluctuation spectroscopy was used to detect particle motion within the pericardial organ of the crab Carcinus while it was perfused with media with increased potassium concentrations. Replacement of some or all of the sodium ions of the normal medium with potassium ions caused a graded increase in motion. Evidence is presented which indicates that this effect is not a consequence of membrane depolarization or calcium ion influx, but is due to the flux of potassium chloride and water into the cytoplasm of the cells.

Animals