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Biomedical subjects

D Elliott

Publications and source records attributed to D Elliott.

At least 181 records · Page 10Linked to original sources
PubMed1979

Multiple birth risk factors and the distribution of handedness.

In this study, we attempted to maximize the likelihood of replicating Bakan's (1971, 1977a) observations that left-handedness was more probable in college students who were the progeny of "high-risk" births. To do this, the relationships between handedness and a combination of factors known to be associated with birth risk were computed. The observed relationships proved to be trivial and thus the validity of Bakan's hypothesis was questionned.

Adult↗
PubMed1977

Cytofluorometric analysis of the kinetics of lymphocyte transformation after phytohemagglutinin stimulation: comparison with the kinetics of thymidine incorporation.

The technique of flow cytofluorometry has been employed to assess the response of unfractionated and highly purified human lymphocyte subpopulations to phytohemagglutinin (PHA) and pokeweed mitogen. Normal values for cytofluorometric responses were established and compared to the uptake of tritiated thymidine in simultaneous experiments. Cytofluorometric analysis offered the advantages of increased sensitivity and direct measurement of DNA content per cell, and provided percentages and absolute numbers of responding cells. B-cell responses to pokeweed mitogen were absent, but brisk T-cell responses were noted. Between 4% and 8% of highly purified human B cells were found to respond to PHA by increasing their DNA content; modest but significant uptake of tritiated thymidine by B cells following PHA stimulation was also observed.

B-Lymphocytes↗
PubMedDate not supplied

The chronic expanding intracerebral hematoma.

Three normotensive patients presented with seizures and CT showed an intracerebral hematoma. Although these patients had no more seizures and developed no other neurological deficit, repeat CT scans (performed 2 to 3 weeks later) showed hematoma enlargement. Angiogram was performed in 2 cases and showed no evidence of vascular malformation or neoplasm. Six weeks to 6 months later, CT showed that the hematoma had changed from a hyperdense to an isodense appearance and in two cases slight enhancement occurred. During a follow-up interval of 6 to 24 months, no other neurological episodes have occurred. The etiology of the chronic expanding intracerebral hematomas was not delineated in these 3 patients.

Adult↗
PubMedDate not supplied

Intraventricular hemorrhage in adults: clinical-computed tomographic correlations.

The clinical and computed tomographic (CT) findings in 100 consecutive adult nontraumatic intraventricular hemorrhage (IVH) cases are analyzed. There were 74 parenchymal brain hemorrhages with secondary ventricular extension. The ventricles were filled with blood and asymmetrically enlarged. If the hemorrhage involved putamen, cerebellum, pons, or subcortical cerebral hemispheric white matter, IVH was associated with large parenchymal hematomas; these patients had poor clinical outcome. With thalamic or caudate hematomas, IVH frequently occurred with large hematomas but may occur with small hematomas. The small hematomas were located directly contiguous to the ventricular walls and caused extensive ventricular blood. Patients with small thalamic and caudate hemorrhage with intraventricular blood had good clinical outcome; whereas patients with large hematomas had poor outcome. Primary IVH occurred in 24 cases. In these cases, blood was seen in all ventricular chambers. Aneurysms involving the anterior cerebral-anterior communicating artery region were the most common etiology for primary IVH.

Adult↗
PubMedDate not supplied

Nontraumatic posterior temporal lobe hemorrhage: clinical computed tomographic correlations.

Ten patients with nontraumatic posterior temporal hematomas were analyzed. These hemorrhages were spontaneous (four cases) or hypertensive (six cases). With right posterior temporal hematomas, headache and confusion of sudden onset were the initial common characteristic clinical signs. The absence of prominent lateralizing neurological deficit simulated a diffuse toxic or metabolic encephalopathy. With left-sided hematomas, Wernicke-type aphasia was the initial feature. The 10 hematomas were 1.8 to 2.8 cm in maximal diameter. In these 10 cases, clinical outcome was good, as all patients survived and the hematoma resolved spontaneously.

Aphasia↗
PubMedDate not supplied

Massive putaminal-thalamic nontraumatic hemorrhage.

Fourteen patients developed massive putaminal-thalamic hemorrhage. All patients were young black men. They were hypertensive but without chronic hypertensive vascular changes. They had been treated with antihypertensive medication for less than 3 yr. All patients presented with a prodromal headache beginning 18-30 h before the brain hemorrhage. Initial clinical signs were heralded by a change in the headache pattern and vomiting. All patients became comatose and hemiplegic within 4-12 h. CT showed a hyperdense putaminal-thalamic hemorrhage which was 60 to 86 mm in maximal diameter. There was marked mass effect with secondary intraventricular extension. All patients died within 72 h, despite rapid and adequate blood pressure control and maximal medical treatment of cerebral edema and increased intracranial pressure.

Adult↗
PubMedDate not supplied

Young Investigator Award. Percutaneous facet joint fusion: preliminary experience.

PURPOSE: The synovium-lined apophysial joint is an important cause of back pain through facet arthrosis and nerve root pressure. The short-term results of two relatively noninvasive treatments--facet block and facet rhizotomy--have been better than their long-term results. The authors propose treatment with fusion of the posterior facet joints in the lumbar spine by means of a simple percutaneous procedure performed under local anesthetic with use of radiologic guidance. MATERIALS AND METHODS: In the first phase of this study the technical feasibility of the concept was established in human cadaver spine. In the second phase a canine model was tested in which bone grafts were surgically inserted into lumbar facet joints. Five male and two female mongrel dogs, weighing 18-25 kg (mean, 20.3 kg), were operated on. Each procedure was done in three steps: First, preoperative computed tomographic (CT) scans were obtained to measure facet depth. Second, surgery was performed under fluoroscopic guidance with use of a threaded guide wire, a small cannulated coaxial drilling system, and hydroxyapatite cancellous bone plugs. Third, early postoperative CT scans were obtained to verify bone plug location. CT was repeated at 4 and 6 months after surgery to check for fusion. The dogs were killed at 6 months, and histologic examination was performed. RESULTS: Successful insertion of the bone plug was achieved in 12 of the 14 facets (86%). One dog died as a complication of the procedure. Fusion occurred in five of the 12 surgically treated facets (42%). CONCLUSION: Drilling and surgical insertion of bone plugs into facet joints of dogs were feasible. The fusion results are promising and may improve with future modifications of the technique.

Anesthesia, Local↗
PubMedDate not supplied

Maintaining clinical excellence in a weekend alternative program: the role of the divisional clinical manager.

Many innovative management changes designed to promote clinical excellence and scholarship were undertaken by the nursing executive team at our 821-bed tertiary care teaching hospital. Included in these changes was the creation of the divisional clinical manager (DCM). The purpose of this article is to describe how these weekend managers employees contribute to the overall objectives of providing consistent supervision, clinical support and a rich continuing education program.

Consultants↗
PubMedDate not supplied

Development and implementation of an instrument measuring CNCs' activities.

This report describes the development and introduction of a 'Clinical Nurse Consultant Activity Report' for use within the nursing division at a major metropolitan teaching hospital. The project involved the designing of an appropriate reporting format and definitions that could encompass all clinical nurse consultants' professional activities. Following the Report's development, an intensive education program was conducted, the Report was successfully trialled and evaluated and some minor modifications were made.

Humans↗
PubMedDate not supplied

Helping people with learning disabilities to handle grief.

This paper examines the scope for using bereavement counselling as an intervention for people with learning disabilities who have experienced a bereavement. It discusses a range of practical measures which can be introduced and highlights the indicators which suggest that interventions are needed.

Attitude to Death↗
PubMedDate not supplied

The role and use of support personnel.

In 1991 a research team from the University of Alberta was given the go-ahead by the National Health Research and Development Program, Health and Welfare Canada to investigate the role and use of support personnel in the rehabilitation disciplines and to provide a preliminary database in nursing. Below, the study findings on the future use, supervision and training of support personnel.

Alberta↗