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Biomedical subjects

D E Strandness

Publications and source records attributed to D E Strandness.

At least 235 records · Page 13Linked to original sources

The effects of femoropopliteal vein graft failure on limb function.

Twenty-one patients were followed for an average of 40 months following occlusion of femoropopliteal vein grafts. Serial recordings of the resting ankle pressure index and treadmill walking time were correlated with the patient's clinical status, and compared to the preoperative values. Graft failure resulted in a return to preoperative status in ten of 11 limb salvage patients. There were 5 amputations, 3 died of unrelated causes, and 2 were subsequently improved by further reconstructions. At last followup, 3 of 10 patients who were operated on for claudication were unchanged, 6 were improved, and one became worse. In no case did graft failure result in the development of advanced ischemia. Femoropopliteal graft failure did not have a significantly adverse effect on limb function or survival in patients presenting with claudication, nor did it complicate the subsequent course of patients in whom the initial aim was limb salvage.

Adult↗

The accuracy of the supraorbital Doppler examination in the diagnosis of hemodynamically significant carotid occlusive disease.

The supraorbital Doppler technique was used to study 102 carotid arteries prior to arteriography. A carotid stenosis was defined as being hemodynamically significant if the diameter of the lumen were reduced by more than 50 percent. The Doppler examination gave a false-positive result in only two of the 61 arteries which did not demonstrate significant stenoses. False-negative Doppler results occurred in 22 percent of the 41 significant carotid lesions. The presence or absence of significant carotid lesions were predicted in 96 percent of 67 arteries for which the results of the supraorbital examination and carotid auscultation were in agreement. False-negative results occurred in association with significant ipsilateral external and common carotid stenoses and in the presence of unusually efficient collateral circulation via the circle of Willis. The supraorbital Doppler examination is a valuable technique for the identification of patients with hemodynamically significant carotid stenoses.

Adult↗

Noninvasive ultrasonic carotid angiography: prospective validation by contrast arteriography.

Pulsed ultrasonic images of the carotid bifurcation in 82 vessels of 43 patients were compared independently with contrast arteriograms for stenosis (by percentage quartiles) or occlusion of the internal carotid artery. All 14 occluded vessels were identified correctly by ultrasound but were visualized on repeat examination. Estimation of percentage stenosis on ultrasonic images agreed with the quartile determination by contrast arteriography in 35 of 68 (51 percent) vessels and was within one quartile of correct interpretation in 48 of 68 (71 percent). The interpretative error of grading stenosis of ultrasonic images was due to vascular wall calcification which inhibited ultrasound transmission. This limitation was overcome by sound spectral (sonographic) analysis of distal internal carotid flow velocity which allowed estimation of stenosis within one quartile of that determined by contrast arteriography in 46 of 47 (98 percent) vessels.

Adult↗

Differntiation of primary from secondary varicose veins by Doppler ultrasound and strain gauge plethysmography.

The Doppler ultrasonic velocity detector and the strain gauge plethysmograph were used to differentiate qualitatively and quantitatively primary from secondary varicose veins. Studies were performed in 21 limbs of 14 normal persons, nine limbs of eight patients with varices secondary to deep venous disease. The latter group of patients was identified by ultrasonic evidence of venous reflux through imcompetent deep venous valves. There was no significant difference in the maximum venous outflow of the limbs of the three groups of persons as determined by plethysmography. The primary hemodynamic abnormality in patients with varicose veins was significant venous reflux through imcompetent venous valves. This reflux was obliterated by tourniquet compression of the varices in patients with primary varicose veins. However, secondary varicose veins are distinguished by persistent abnormal deep venous reflux after compression of the varices. These diagnostic techniques not only provide accurate noninvasive diagnostic information but also may facilitate determination of prognosis and therapy of patients with varicose veins.

Adult↗

The transcutaneous measurement of the elastic properties of the human saphenous vein femoropopliteal bypass graft.

The pressure-strain elastic modulus and compliance of 20 reversed saphenous femoropopliteal vein grafts have been measured by a noninvasive, ultrasonic method. The grafts had been in place for an average of 33.6 months, 11 days to 128 months. In this study no correlation was demonstrated between wall stiffness and duration of implantation. It is concluded that the elastic properties of vein grafts may remain stable for considerable periods of time.

Adult↗