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Biomedical subjects

D E Ryan

Publications and source records attributed to D E Ryan.

At least 127 records · Page 7Linked to original sources

Dantrolene sodium in the management of patients at risk from malignant hyperthermia.

Malignant hyperthermia is a dominantly inherited, usually subclinical, disease that occurs in individuals who have an underlying muscular disorder and connotes the gravest possible consequences. When it occurs, it is usually during the use of muscle relaxants in anesthesia and potent anesthetic agents such as halothane. Patients at risk must be identified through careful history and screening procedures; however, a patient susceptible to this condition may have had general anesthesia in the past without complications. A careful monitoring regimen must be established for the procedure and some means of cooling the patient must be ready in case pyrexia occurs. Dantrolene sodium is currently the preferred drug for prevention of the syndrome and may be valuable for its treatment.

Adult↗

A modified approach to the ilium to obtain graft material.

The ilium is a commonly utilized site for obtaining graft material for maxillofacial reconstruction. Pain, decreased mobility, and equivocal esthetics are complications sometimes encountered postoperatively with most current ilium harvesting techniques. A new approach to the ilium for obtaining marrow and cancellous bone was used in 26 cases during a one-year period. No complications encountered in the donor site. The technique is simple, allows simultaneous procedures, and is esthetically acceptable.

Curettage↗

Trace elements in scalp-hair of persons with multiple sclerosis and of normal individuals.

Scalp-hair samples from 40 multiple sclerosis patients and 42 controls were analyzed by neutron activation analysis, with a SLOWPOKE reactor as the neutron source. Ag, Al, As, Au, Ba, Br, Ca, Cl, Cu, l, K, Mg, Mn, Na, S, Sb, Se, Sr, V, and Zn were determined in samples of about 0.1 g. Highly significant differences (99% confidence) were observed between the two groups in concentrations of Cu, l, Mn, S, Se, and V.

Adult↗

An appliance that permits early mobilization after correction of mandibular prognathism.

With certain orthognathic surgery patients, such as epileptics, severe asthmatics, or those with other medical problems that increase risk during intermaxillary fixation, there occasionally may be an indication for a reduced fixation time. By using Vitallium mesh for stability, immobilization for 2 to 2 1/2 weeks has proved to be sufficient in a limited number of cases. Mobilization before two weeks has not been attempted. The procedure, however, is not recommended as a routine method of fixation.

Humans↗