Biomedical subjects

D E Rizk

Publications and source records attributed to D E Rizk.

41 records · Page 3Linked to original sources

PubMed1995

Subdermal levonorgestrel implants. Three years' experience in Cairo, Egypt.

OBJECTIVE: To assess the efficacy, safety and acceptability of the subdermal levonorgestrel implant (SLI), a new, long-acting, low-dose, progestin-only contraceptive method for women. STUDY DESIGN: A prospective, observational study conducted in the family planning clinic, Department of Obstetrics and Gynecology, Ain Shams University Hospital, Cairo, Egypt, as an advanced phase III clinical trial. RESULTS: This paper describes three years' experience with the SLI in 350 women. The net three-year cumulative pregnancy rate was 0.98%. Menstrual disturbances, ranging from amenorrhea to menorrhagia, were the major side effects and were present in 25% of women during the third year. These disturbances resulted in 28 removals, 19 of which were because of amenorrhea. Medical complications, including headache, hypertension and non-insulin dependent diabetes; desire for pregnancy; and complications at the insertion site (such as infection, spontaneous expulsion of the capsules and arm pain) were the principal reasons for another 57 implant removals. So far, no gynecologic or breast lesions have developed, and weight changes were not noted. The continuation rate after three years was 65.5%. CONCLUSION: The efficacy, safety and acceptability of the implant suggest that it will provide an important addition to the contraceptive armamentarium.

Administration, Cutaneous↗

PubMed1994

Maternal steroid sulfatase deficiency--cause of high-risk pregnancy?

A pregnancy is described in a woman with X-linked steroid sulfatase deficiency and an unaffected but growth-retarded male fetus. Her previous affected pregnancy that resulted in intrauterine fetal death was reported. Urinary estriol estimation in pregnancy is discussed.

Arylsulfatases↗

PubMed1994

Congenital subglottic laryngeal stenosis presenting with fetal distress and resulting in neonatal death.

Explore the source record for details and available documents.

Adult↗

PubMed1993

Placental sulfatase deficiency and congenital ichthyosis with intrauterine fetal death: case report.

Placental sulfatase deficiency and congenital ichthyosis are two manifestations of an X-linked recessive inborn error of metabolism. This uncommon disorder can be diagnosed antenatally by maternal urinary steroid assays. A case with an affected sibling is presented, and the disorder's association with fetal death and failure to induce labor is discussed.

Adult↗

PubMed1993

Isolated complex limb reduction abnormality diagnosed antenatally.

Congenital limb reduction defects are rare lesions that are usually associated with other anomalies. Terminal defects are the commonest reduction defects. The aetiology seems to be multifactorial. We present a case of congenital terminal deficiency of the same side of the upper and lower limbs diagnosed by ultrasound scanning during the second trimester. The fetus had an absent right fibula and right foot, a hypoplastic right hand and left talipes equinovarus. The pregnancy was terminated. Micrognathia was the only associated anomaly found on postmortem examination. The cause of this isolated anomaly is unknown but, because of the very variable presentation of limb reduction defects, could possibly fit into the categories so far described in the literature.

Adult↗