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Biomedical subjects

D E Janelli

Publications and source records attributed to D E Janelli.

9 recordsLinked to original sources

Malignant fibrous histiocytoma of the colon associated with diverticulitis.

We report the second case of a malignant fibrous histiocytoma of the large bowel. The neoplasm constituted an incidental finding during the diagnostic work-up for diverticulitis of the sigmoid colon. There was a massive abdominal recurrence of the tumor four months after colectomy, and the patient died nine months after the initial operation. The literature on fibroblastic sarcomas of the colon is also reviewed.

Aged↗

Adrenal ablation.

Of 135 patients who had bilateral adrenalectomies for metastatic breast cancer, 110 could be evaluated and 63 patients (57.3%) responded (43 objective, 20 subjective responders). Patients aged 31 to 45 years had a 56% response rate; 58% of patients aged 46 to 70 responded. Oophorectomy responders benefited from adrenalectomy 62% of the time and oophorectomy failures reponded in 38% of the cases. Patients with a disease-free interval of zero to 2.5 years responded to adrenalectomy at a rate of 46%, whereas patients with a free interval greater than 2.5 years responded at a rate of 73%. The median survival rate of 63 adrenalectomy responders was 28 months; it was ten months for 47 nonresponders.

Adrenalectomy↗